DK Golwala, LD Patel, SB Bothara, SK Vaidya, AR Sahu, S Kumar
DK Golwala1*, LD Patel2, SB Bothara1, SK Vaidya 1, AR Sahu1 and S Kumar3
1C.U. Shah College of Pharmacy and Research, Wadhwan, Gujarat, India.
2 SAL Institute of Pharmacy, Sola-Bhadaj Road, Ahmedabad, Gujarat, India.
3 GHB College of Pharmacy, Anayad, Panchmahal, Gujarat, India.
Volume - 3,
Issue - 1,
Year - 2010
The present study reveal that the ethanolic and aqueous extracts of Abutilon indicum Leaf using two different doses of each extract in acute (Carrageenin induced hind paw edema) and subacute (Formaldehyde induced hind paw edema) inflammation induced in rats, p.o. administration. In acute inflammation the % protection AIE 300 mg/kg - 64.04 % and 100 mg/kg - 59.55%, while AIA 300 mg/kg - 46.66 % and 100 mg/kg - 32.88 %. In Subacute inflammation the % protection in 3rd h are AIE 300 mg/kg - 86 % and 100 mg/kg - 68 %, while AIA 300 mg/kg - 68 % and 100 mg/kg - 44 %.The % protection of both the extracts shows Abutilon indicum possess potent anti-inflammatory activity and it significantly reduces inflammation.
Cite this article:
DK Golwala, LD Patel, SB Bothara, SK Vaidya, AR Sahu, S Kumar. Anti-Inflammatory Activity of Abutilon indicum Linn. Leaf. Research J. Pharm. and Tech. 3(1): Jan.-Mar. 2010; Page 183-186.