Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Treatment for the management of Obsessive-Compulsive Disorder in Children: A Review

Author(s): Uday Gaikwad, Milind Parle

Email(s): uduraj2003@gmail.com

DOI: Not Available

Address: Uday Gaikwad* and Milind Parle
Pharmacology Division, Dept. Pharm. Sciences, Guru Jambheshwar University of Science and Technology, Post Box-38, Hisar-125 001, Haryana, India
*Corresponding Author

Published In:   Volume - 3,      Issue - 1,     Year - 2010

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ABSTRACT:
Obsessive-Compulsive Disorder (OCD) is characterized by absurd, recurrent and persistent thoughts (obsessions) followed by certain stereotyped actions (compulsions). Obsessive-Compulsive disorder can impair all areas of brain functioning and produce devastating effects on patients and their families. Therefore, there is necessity to aware about the OCD in children and different treatments for its management. The Group A Beta–Hemolytic Streptococcal (GABHS) infections produce antineuronal antibodies that adversely affect basal ganglia cells might play part in etiology of OCD in children. As a result of obsessions, (usually obsessions concerning dirt and contamination, or fear of harming others), many children with OCD develop an avoidant behavior. The newer generation of antidepressant drugs viz. fluvoxamine, fluoxetine, paroxetine, sertraline and citalopram have also been found useful in management of OCD. Neurosurgical treatments have been used for the management of chronic, severely distressing forms of OCD where conventional treatments are ineffective. Psychopharmacological treatments have also been found useful in reduction of repetitive unpleasant behavior. Pharmacological and psychopharmacological treatments combinely have been providing strong effective management of in vivo serotonin impairment as well as reduction of repetitive unpleasant behavior which account for characteristics of OCD.


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Cite this article:
Uday Gaikwad, Milind Parle. Treatment for the management of Obsessive-Compulsive Disorder in Children: A Review. Research J. Pharm. and Tech. 3(1): Jan.-Mar. 2010; Page 66-68.


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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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