Author(s): NB Ghiwarem, TM Nesari

Email(s): ashish_roge@rediffmail.com

DOI: Not Available

Address: NB Ghiware1* and TM Nesari2
1Department of Pharmacology, Nanded Pharmacy College, Nanded-431605, India
2Department of Dravyaguna, Tilak Ayurved Mahavidyalaya, Pune-411011, India
*Corresponding Author

Published In:   Volume - 3,      Issue - 1,     Year - 2010


ABSTRACT:
Acute oral toxicity studies of the Piper nigrum Linn (Family: Piperaceae), and Nyctanthes arbor-tristis Linn (Family: Oleaceae), were carried out in rats. All external morphological changes, change in body weight, general systemic toxicity and necropsy were recorded. During acute toxicity study there was normal weight gain in the treatment group was observed. There were no significant signs of systemic toxicity and death was noted. No abnormalities were noted at necropsy. Tablet, liquid oral and suspension dosage forms of dried unripe fruits of Piper nigrum and dried leaves of Nyctanthes arbor-tristis in combination, were tested in brewer’s yeast-induced pyrexia in rabbits to assess their antipyretic activity. The percent inhibition rate against increasing rectal temperature in rabbits was assessed for all test dosage forms and was found significant compared to that of control. The results indicate that liquid oral and tablet dosage forms possess good antipyretic property compared to suspension dosage form.


Cite this article:
NB Ghiwarem, TM Nesari. Antipyretic Activity of Piper nigrum and Nyctanthes arbor-tristis in Different Dosage Forms. Research J. Pharm. and Tech. 3(1): Jan. - Mar. 2010; Page 157-160


Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags