Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)


Submit Article

Hypoglycemic Activity of Curculigo orchioides Gaertn in Normal and Streptozotocin Induced Diabetic Rats

Author(s): AK Jain, Naveen Sharma, Amit Upadhyay, Ashish Dixit

Email(s): naveesharma123@yahoo.co.in

DOI: Not Available

Address: AK Jain1, Naveen Sharma2*, Amit Upadhyay2 and Ashish Dixit2
1G.R.Medical College, Gwalior, M.P.
2Shri RNS Inst. of Pharmaceutical Science and Technology, Sithouli, Gwalior.M.P.-474015
*Corresponding Author

Published In:   Volume - 3,      Issue - 1,     Year - 2010

 View HTML        View PDF

ABSTRACT:
The purpose of this study was to study effects of Curculigo orchioides Gaertn rhizome on blood glucose level. The antihyperglycemic efficacy of ethanolic extract of the rhizome was evaluated in normal and streptozotocin-induced diabetic rats (STZ diabetic rats). The extract exhibited significant hypoglycemic activity when compared with the control group and to that of the effect produced by a standard antidiabetic agent Glibenclamide. The result also indicated dose dependent effect. The hypoglycemic effect produced by the extract may be due to the uptake of glucose at the tissue level or inhibition of intestinal absorption of glucose. We conclude that ethanolic extract of Curculigo orchioides Gaertn is a potential hypoglycemic agent and lends scientific support for its use in folk medicine.


Keywords:

Cite this article:
AK Jain, Naveen Sharma, Amit Upadhyay and Ashish Dixit. Hypoglycemic Activity of Curculigo orchioides Gaertn in Normal and Streptozotocin Induced Diabetic Rats. Research J. Pharm. and Tech. 3(1): Jan. - Mar. 2010; Page 133-135.

Cite(Electronic):
AK Jain, Naveen Sharma, Amit Upadhyay and Ashish Dixit. Hypoglycemic Activity of Curculigo orchioides Gaertn in Normal and Streptozotocin Induced Diabetic Rats. Research J. Pharm. and Tech. 3(1): Jan. - Mar. 2010; Page 133-135.   Available on: https://rjptonline.org/AbstractView.aspx?PID=2010-3-1-20


Recomonded Articles:

The Use of Neem in Oral Health

Author(s): Niha Naveed, Karthikeyan Murthykumar, Subasree Soundarajan, Sripradha Srinivasan

DOI: Not Available         Access: Open Access Read More

Neermulli kudineer – A Classical Polyherbal Decoction in Siddha System of Medicine

Author(s): A. Rajendra Kumar, N. J. Muthukumar, A. Faridha

DOI: 10.5958/0974-360X.2019.00081.7         Access: Open Access Read More

Antidiabetics Review on Natural Products

Author(s): Surendra Nath Pandeya, Rajeev Kumar, Arun Kumar, Ashish Kumar Pathak

DOI: Not Available         Access: Open Access Read More

A Review on Antioxidant activity of Psidium guajava

Author(s): R. Manikandan, A. Vijaya Anand

DOI: 10.5958/0974-360X.2015.00056.6         Access: Open Access Read More

Hypoglycemic Activity of Curculigo orchioides Gaertn in Normal and Streptozotocin Induced Diabetic Rats

Author(s): AK Jain, Naveen Sharma, Amit Upadhyay, Ashish Dixit

DOI: Not Available         Access: Open Access Read More

Evaluation of Hypoglycemic activity of different extracts of Bombax ceiba L. leaves

Author(s): S. Bhargava, M.B. Shah

DOI: 10.5958/0974-360X.2016.00036.6         Access: Open Access Read More

Study of Antidiabetic Activity of Cow Urine and Its Concentrate

Author(s): S. P. Wate, N. J. Duragkar, M. R. Tajne, S. S. Jadhav

DOI: Not Available         Access: Open Access Read More

Anti-Hyperglycemic and Antioxidant Activities of the Mehari Choornam

Author(s): Sanap GS, Sawant VA, Shende VS, Shid SL, Borkar SN, Tarannum S, Dama GY, Suresh R

DOI: Not Available         Access: Open Access Read More

Simultaneous Spectrophotometric Estimation and Validation of Metformin Hydrochloride and Glibenclamide in Bulk Drug and Pharmaceutical Dosage Form

Author(s): B Srivastava, Uttam Singh Baghel, Pradeep Swarnkar and Shuchi Dave

DOI: Not Available         Access: Open Access Read More

Synthesis and Antihyperglycemic Activity of Novel 6,7,8,9 Tetra Hydro-5H-5-Phenyl-2-Benzylidine-3-Substituted Hydrazino Thiazolo (2, 3-B) Quinazoline Derivatives and Analogues

Author(s): Theivendren Panneer Selvam, Palanirajan Vijayaraj Kumar

DOI: Not Available         Access: Open Access Read More

Effect of Some Penetration Enhancers on In-vitro Permeation of Glibenclamide

Author(s): SD Pande, SB Joshi, SB Kasture, VM Aurangabadkar

DOI: Not Available         Access: Open Access Read More

Anti-Hyperglycemic activity of the Leaves of Terminalia tomentosa against Normal and Alloxan Induced Diabetic Rats

Author(s): Sravanthi.Alladi, Sarath Prakash D., Ramesh Malothu, Nalini M., Srikanth Rao K.

DOI: Not Available         Access: Open Access Read More

An Overview of Treatment Challenges and the role of Herbal Antioxidants in Diabetes Mellitus

Author(s): Krishna Ravi, Rosmi Jose, Sumitha SK, Teena Johny, Krishnaveni K, Shanmuga Sundaram R, Sambath Kumar R

DOI: 10.5958/0974-360X.2017.00490.5         Access: Open Access Read More

An Appraisal of Pharmacological actions of Morus indica: The Indian mulberry with a detailed investigation on its Anti-diabetic potential

Author(s): Flowerlet Mathew, Bimi Varghese, Dhanish Joseph, Manju Maria Mathews, Betsy Sunny, Junia George

DOI: 10.5958/0974-360X.2019.00623.1         Access: Open Access Read More

Formulation Development and Evaluation of Glibenclamide Microcapsules Using Solvent Evaporation Technique

Author(s): Shivhare UD, Kale MK, Bhusari KP, Madankar VS, Godbole MD

DOI:         Access: Open Access Read More

Formulation and Evaluation of Controlled Release Microspheres Containing Metformin Hydrochloride

Author(s): UK Patil, Ravish Sahu, SK Yadav

DOI:         Access: Open Access Read More

Tamarix aphylla L.: A Review

Author(s): Thamer Mouhi Jasiem, Noor Mohsen Nasser, Huda K. AL-Bazaz

DOI: 10.5958/0974-360X.2019.00541.9         Access: Open Access Read More

Effects of Manilkara hexandra on blood glucose levels of normal and Alloxan induced diabetic rats

Author(s): NimbekarT.P., Katolkar P.P., Patil A.T.

DOI: Not Available         Access: Open Access Read More

Synthesis of Novel molecular hybrid 3-(4,5-dihydro-1H-pyrazol-3-yl)-4-hydroxy-2H-chromen-2-one derivatives and In Vitro α-glucosidase and α-amylase inhibitory activity

Author(s): Vikas N. Telvekar, Krishna N. Mundlod, Ghanshyam B. Jadhav, Navnath T. Hatvate, Shrikant M. Ghodse

DOI: 10.5958/0974-360X.2020.00798.2         Access: Open Access Read More

Antihyperglycemic activity of ethanolic extract of leaves of Dioscorea japonica in STZ-induced diabetic rats

Author(s): Budhwani Ashok K., Shrivastava B., Singhai A.K., Gupta Prashant

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus

SCImago Journal & Country Rank

Quick Links

Latest Issues

Popular Articles


Recent Articles



The Effect of Apis mellifera Propolis on RUNX-2 and ALP during Remodeling of Orthodontic Tooth movement
Characterization of Microbial pigments from a combination of Citrus limon peel and Carica papaya pulp extract by using Penicillium purpurogenum.
Different Methods of Preparation, Evaluation and Comparison of One Traditional Oral Liquid Formulation for Potential Antihyperlipidemic Activity in Hyperlipidemic Wistar Rats
Analytical Method Development and Validation of Stability Indicating assay method of analysis for Dolutegravir/Lamivudine/Tenofovir Disoproxil Fumarate tablets using High Performance Liquid Chromatography
Analytical Method Development and Validation of Glipizide to Determine Residual solvents by head Space-Gas Chromatography.
Formulation and Evaluation of Medicated Chewing gum consisting of Dextromethorphan and Guaifenesin for the treatment of cough.
In-vitro Antioxidant, Antidiabetic, Antibacterial and Cytotoxic Activities of Essential Oil extracted from Flowers of Illicium verum L.
Estimation of Ceftazidime and Avibactam in their Bulk and Formulations by a newly Developed and Validated of Stability Indicating RP-UPLC Method.
Association of Serum Renal Function Levels with Heart Failure Disease in Iraqi Patients.
Stability Indicating Simultaneous Estimation of Cetirizine Hydrochloride and Phenylephrine Hydrochloride in Combined tablet formulation by using HPTLC- Densitometric method
Neuroprotective potential of Cilostazol in 3-NP provoked Huntington
Formulation, Design and Optimization of Glycerosomes for Topical Delivery of Minoxidil.
GC-MS Analysis of n-hexane Extract of Roots of Aerva lanata (Linn) Juss. ex. Schult
Cold cream combination of Garcinia mangostana L. Anredera cordifolia (Ten.) and Centella asiatica extracts on Burn Healing Activity Test
Evaluation of Acute, Subacute and LD50 values of Methanolic extract of Sphaeranthus indicus leaves in Albino mice.
Method Development and Validation of Simultaneous Estimation of Emtricitabine and Tenofovir Alafenamide in Bulk and tablet Dosage form using LC-MS/MS.
Simultaneous Spectrophotometric Estimation of Paroxetine Hydrochlorides and Clonazepam in Bulk and Tablet Dosage Form.
Study of Development problems dynamics of Ukrainian market of stomach ulcer treatment drugs
Serum Uric Acid, Lipid Profile and Atherogenic Index of Plasma in Dipper and Non-dipper Normotensive Subjects
Phylogeny Analysis of gyrB Gene and 16S rRNA Genes of Pseudomonas aeruginosa Isolated from Iraqi Patients.

Tags


About Journal

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
Read More  

Visitors

Today: 12798
Yesterday: 17574
Total: 7698018