Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Hypoglycemic Activity of Curculigo orchioides Gaertn in Normal and Streptozotocin Induced Diabetic Rats

Author(s): AK Jain, Naveen Sharma, Amit Upadhyay, Ashish Dixit

Email(s): naveesharma123@yahoo.co.in

DOI: Not Available

Address: AK Jain1, Naveen Sharma2*, Amit Upadhyay2 and Ashish Dixit2
1G.R.Medical College, Gwalior, M.P.
2Shri RNS Inst. of Pharmaceutical Science and Technology, Sithouli, Gwalior.M.P.-474015
*Corresponding Author

Published In:   Volume - 3,      Issue - 1,     Year - 2010

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ABSTRACT:
The purpose of this study was to study effects of Curculigo orchioides Gaertn rhizome on blood glucose level. The antihyperglycemic efficacy of ethanolic extract of the rhizome was evaluated in normal and streptozotocin-induced diabetic rats (STZ diabetic rats). The extract exhibited significant hypoglycemic activity when compared with the control group and to that of the effect produced by a standard antidiabetic agent Glibenclamide. The result also indicated dose dependent effect. The hypoglycemic effect produced by the extract may be due to the uptake of glucose at the tissue level or inhibition of intestinal absorption of glucose. We conclude that ethanolic extract of Curculigo orchioides Gaertn is a potential hypoglycemic agent and lends scientific support for its use in folk medicine.


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Cite this article:
AK Jain, Naveen Sharma, Amit Upadhyay and Ashish Dixit. Hypoglycemic Activity of Curculigo orchioides Gaertn in Normal and Streptozotocin Induced Diabetic Rats. Research J. Pharm. and Tech. 3(1): Jan. - Mar. 2010; Page 133-135.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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