Author(s): Shradhanjali M Singh, Kirti S Topagi, Mrinalini C Damle

Email(s): mcdamle@rediffmail.com

DOI: Not Available

Address: Shradhanjali M Singh, Kirti S Topagi, and Mrinalini C Damle*
Dep. of Pharmaceutical Chemistry, A.I.S.S.M.S. College of Pharmacy, Kennedy Road, Near R.T.O., Pune – 411001.
*Corresponding Author

Published In:   Volume - 2,      Issue - 4,     Year - 2009


ABSTRACT:
A simple, fast, accurate and precise method has been developed for the simultaneous determination of Ramipril and Valsartan from pharmaceutical formulation by reverse phase high performance liquid chromatography (RP-HPLC). The separation was carried out on Hypersil gold CN column using Acetonitrile and Water [pH adjusted to 3.0 with Orthophosphoric acid (0.08%)] in the ratio (70:30v/v). The retention times of Ramipril and Valsartan were 5.08 ? 0.02 and 3.68 ? 0.02 minutes respectively. The developed method was validated as per ICH Guidelines.


Cite this article:
Shradhanjali M Singh, Kirti S Topagi, Mrinalini C Damle. A Validated RP-HPLC Method for Simultaneous Determination of Ramipril and Valsartan in Pharmaceutical Formulation. Research J. Pharm. and Tech.2 (4): Oct.-Dec. 2009; Page 749-752.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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