Author(s): Abhishek K Jain, C. P. Jain, Anshu Sharma

Email(s): abhi181281@yahoo.com

DOI: Not Available

Address: Abhishek K Jain*, C. P. Jain and Anshu Sharma
University Dept. of Pharmaceutical Sciences, M.L.S. University, Udaipur, Rajasthan
*Corresponding Author

Published In:   Volume - 2,      Issue - 4,     Year - 2009


ABSTRACT:
An accurate, simple, reproducible and sensitive method for the determination of paracetamol was developed and validated. Paracetamol was identified using a , Microsorb-MV 100-5 C18 column (250 x 4.6 mm; North America) by binary gradient elution with a flow rate of 0.5 ml/min. The mobile phase composition was methanol: water (30:70) (v/v) and spectrophotometric detection was carried out at 245 nm. The linear range of determination for paracetamol was 0.816-250 µg/ml. The method was shown to be linear, reproducible, specific and sensitive.


Cite this article:
Abhishek K Jain, C. P. Jain, Anshu Sharma. Reverse Phase - High Performance Liquid Chromatography Method for the Analysis of Paracetamol. Research J. Pharm. and Tech.2 (4): Oct.-Dec. 2009; Page701-704.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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