Author(s): Shashikant R Pattan, Syed N Lateef, Prakash N Kendre, Nachiket S Dighe, Rahul K Godge

Email(s): godgerk1@rediffmail.com

DOI: Not Available

Address: Shashikant R Pattan, Syed N Lateef, Prakash N Kendre, Nachiket S Dighe and Rahul K Godge*
Pravara Rural College of Pharmacy, Pravaranagar, Dist. Ahemadnagar (MS), India
*Corresponding Author

Published In:   Volume - 2,      Issue - 3,     Year - 2009


ABSTRACT:
A new sensitive, simple, rapid and precise method for simultaneous estimation of Ofloxacin and Satranidazole in bulk and combined tablet dosage form has been developed. The method is based on ratio derivative Spectrophotometry. The amplitude in first derivative of the ratio spectra at 300 nm and 222 nm (minima) were selected for Ofloxacin and Satranidazole respectively. The concentration range for Ofloxacin and Satranidazole chosen was 2-20 µg/ml and 3-30 µg/ml respectively. The method showed good linearity, accuracy and reproducibility. Results of analysis validated statistically and by recovery studies.


Cite this article:
Shashikant R Pattan, Syed N Lateef, Prakash N Kendre, Nachiket S Dighe, Rahul K Godge. Simultaneous Estimation of Ofloxacin and Satranidazole in Bulk and Dosage form by Ratio Spectra Derivative Spectroscopy. Research J. Pharm. and Tech.2 (3): July-Sept. 2009,;Page 531-533.


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