Author(s): K Girija, Divya Chacko

Email(s): narasimhan_ girija@bsnl.in

DOI: Not Available

Address: K Girija* and Divya Chacko
Mother Theresa Post Graduate and Research Institute of Health Sciences, (A Govt. of Puducherry Institution), Indira Nagar, Gorimedu, Puducherry – 6.
*Corresponding Author

Published In:   Volume - 2,      Issue - 3,     Year - 2009


ABSTRACT:
A series of novel N-substituted piperazinyl fluoro quinolones were synthesized under microwave technology. In the SAR study the aryl substituent’s on the piperazine nitrogen were found to play an important role for the Anti-HIV and cytotoxic activity. Four compounds were synthesized through modifying the N4-hydrogen of the piperazine in fluoroquinol ones with phthalimide. The purity of the synthesized compounds were ascertained by TLC and melting point determination. The structures of the synthesized compounds were screened for their Anti-HIV and invitro cytotoxic activity.


Cite this article:
K Girija, Divya Chacko. Eco-Friendly Synthesis and Biological Evaluation of Some Novel N-Substituted Piperazinyl Fluoro Quinolone Derivatives. Research J. Pharm. and Tech.2 (3): July-Sept. 2009,;Page 498-501.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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