ABSTRACT:
The ethanolic and acetone extracts of Bauhnia variegate bark was examined for anti-inflammatory in experimental animals. In this study both acute and sub-acute inflammation models were used to evaluate the anti-inflammatory activity of the Bauhnia variegate. In acute model carrageenan was used to induce inflammation in rat hind paw and in sub-acute inflammation, cotton pellet induced granuloma was performed. The bark of ethanolic and acetone extracts of bauhnia variegate at the doses of 400 mg/kg shows significant (p<0.001) inhibition of inflammation against both acute and sub-acute anti-inflammatory model. The percentage inhibition of ethanolic and acetone extract of Bauhnia variegate both acute and sub-acute anti-inflammatory model was 35.29%, 43.14% and 33.53%, 42.20% respectively. According to our results both the extracts of Bauhnia variegate in doses of 400 mg/kg reveals anti-inflammatory activity and supports tribal claim.