Author(s): VJ Galani, BG Patel

Email(s): vrp173@yahoo.com

DOI: Not Available

Address: VJ Galani*1, and BG Patel 1
1Department of Pharmacology, A R. College of Pharmacy and GH. Patel Institute of Pharmacy, Vallabh Vidyanagar-388120. Gujarat, India.
*Corresponding Author

Published In:   Volume - 2,      Issue - 2,     Year - 2009


ABSTRACT:
Argyreia speciosa, a woody climber is widely used in ayurveda for the treatment of neurological disorders. This work researched the action of the n-hexane (n-HF), chloroform (CF), ethyl acetate (EAF) and water (WF) fractions of hydroalcoholic extract of roots of Argyreia speciosa on the central nervous system. All the fractions (100, 200 and 500 mg/kg, p.o.) were evaluated for neuro-pharmacological activity using spontaneous motor activity and pentobarbital-induced sleeping time in mice. Chlorpromazine was used as a positive control. Central nervous system depressant activity was observed with all the fractions as indicated by the results in which they reduced spontaneous motor activity and potentiated pentobarbital induced hypnosis in mice. These results suggest that the active principles present in the root of Argyreia speciosa may responsible for central nervous depressant activity.


Cite this article:
VJ Galani, BG Patel. Central Nervous System Activity of Argyreia Speciosa Roots in Mice. Research J. Pharm. and Tech.2 (2): April.-June.2009; Page 331-334.


Recomonded Articles:

Author(s): Harsha. L, Jothi Priya, Khushali. K. Shah, Reshmi. B

DOI: 10.5958/0974-360X.2015.00189.4         Access: Open Access Read More

Author(s): Deivendran Kalirathinam, Albin Jerome, Bhagyashri BhagwanVichare, NareshBaskar Raj, Mahadeva Rao US

DOI: 10.5958/0974-360X.2017.00262.1         Access: Open Access Read More

Author(s): Anupam Roy, Biswajit Das

DOI: 10.5958/0974-360X.2015.00237.1         Access: Open Access Read More

Author(s): Nowshin Nowaz Rumzhum, Mostafizur Rahman, AFM Rafiu-Ul Islam

DOI: Not Available         Access: Open Access Read More

Author(s): Sudharshan SJ, Chinmaya A, Valleesha NC, Prashith Kekuda TR, Rajeshwara AN, Syed Murthuza

DOI:         Access: Open Access Read More

Author(s): Valli G.1, Ramu K.1, Mareeswari P.1 and Thanga Thirupathi A2

DOI: Not Available         Access: Open Access Read More

Author(s): M. Shankar, R. Suthakaran

DOI: Not Available         Access: Open Access Read More

Author(s): Nagarathna PKM, Harsha Vardhini N, Babiker Bashir, Mahesh kumar C S, Chandanam Sreedhar

DOI: 10.5958/0974-360X.2019.00683.8         Access: Open Access Read More

Author(s): Moon R. S., Mitkare S.S., Kshirsagar R.V, Kale A.G., Shinde N.D., Malewar A.S., Pawde P.K.

DOI:         Access: Open Access Read More

Author(s): Sree Lekshmi. R. S, P. Shanmugasundaram

DOI: 10.5958/0974-360X.2018.00659.5         Access: Open Access Read More

Author(s): Soumi Acharya, S. S. Meenambiga

DOI: 10.5958/0974-360X.2020.00354.6         Access: Closed Access Read More

Author(s): Tapas Kumar Mohapatra, Bharat Bhusan Subudhi

DOI: 10.5958/0974-360X.2019.00337.8         Access: Open Access Read More

Author(s): Gayathiri. N. M, Sudhakar P, Manimekalai P, Sabarinath C

DOI: 10.5958/0974-360X.2019.00660.7         Access: Open Access Read More

Author(s): Amruta V. Yadav, Mohd. Bashar Momin, Md. Awais Panjwani

DOI: 10.5958/0974-360X.2020.00559.4         Access: Closed Access Read More

Author(s): S Sreeni, Nafiya Muhammed Zackariah, Lakshmi R

DOI: 10.5958/0974-360X.2017.00212.8         Access: Open Access Read More

Author(s): Hardik B. Rana, Mukesh C. Gohel, Mansi S. Dholakia, Tejal R. Gandhi, Abdelwahab Omri, Vaishali T. Thakkar

DOI: 10.5958/0974-360X.2019.00138.0         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags