Author(s): Tushar Kotkar, Sushant Dhavale, Bhavin Patel, SR Hardikar, Swati Mutha, AV Bhosale

Email(s): kotkar_tushar85@rediffmail.com

DOI: Not Available

Address: Tushar Kotkar*, Sushant Dhavale, Bhavin Patel, SR Hardikar, Swati Mutha, and AV Bhosale
P.D.E.A’s Seth Govind Raghunath Sable College of Pharmacy, Saswad: 412301 Dist: Pune Maharashtra INDIA
*Corresponding Author

Published In:   Volume - 2,      Issue - 1,     Year - 2009


ABSTRACT:
The goal in drug delivery research is to develop formulations to meet therapeutic needs relating to particular pathological conditions. Variation of physiological and pathophysiological functions in time has brought a new approach to the development of drug delivery systems. Research in chronopharmacological field has demonstrated the importance of biological rhythms in drug therapy. Optimal clinical outcome can not be achieved if drug plasma concentrations are constant. If symptoms of a disease display circadian variation drug release should also vary over time. Utilisation of different technologies in development of time-controlled, pulsed, triggered and programmed drug delivery devices has been undergoing recent years. Formulations should be justified by biopharmaceutical and pharmacokinetic study in order to choose the best hour for administration. Another point raised by circadian variation of physiological function is that drug pharmacokinetics can also be time-dependent (i.e. chronopharmacokinetics). Both variations in a disease state and in drug plasma concentration need to be taken into consideration in developing of drug delivery systems intended for treatment of disease with adequate dose at appropriate time.


Cite this article:
Tushar Kotkar, Sushant Dhavale, Bhavin Patel, SR Hardikar, Swati Mutha, AV Bhosale. Chronopharmaceutical Drug Delivery System: A Review. Research J. Pharm. and Tech. 2(1): Jan.-Mar. 2009; Page 58-64.


Recomonded Articles:

Author(s): Nimbalkar V.V., Pansare P.M., Nishane B.B.

DOI: 10.5958/0974-360X.2015.00310.8         Access: Open Access Read More

Author(s): Sonte Sushmitha, Sedimbi Revathi Priyanka, L. Mohan Krishna, M. Srinavasa Murthy

DOI: Not Available         Access: Open Access Read More

Author(s): Raj Kumar R, Praveen D, Palani Shanmugasundaram

DOI: 10.5958/0974-360X.2016.00164.5         Access: Open Access Read More

Author(s): Siripurapu Sriram, Venkata Ravibabu Mandla, Chaithanya Sudha M, Saladi S.V. Subba Rao, Nagaveni Ch, Vani V., Gobinath P., Raj Kumar KVG., Jaydeep Lella, Sannidhi Krishna Praveen, Debjit Datta

DOI: 10.5958/0974-360X.2017.00078.6         Access: Open Access Read More

Author(s): M. Sumithra, Avantika Prabhabanik

DOI: 10.5958/0974-360X.2017.00036.1         Access: Open Access Read More

Author(s): Archana Kushwaha, Jayanti Jaiswal, Priya Singh, Neha Rathore, Jai Prakash Dhruw, Ishu Sahu, Chhaya Singh, Krinsha Kumar Sahu, Mukta Agrawal, D. K. Tripathi, Ajazuddin, Amit Alexander

DOI: 10.5958/0974-360X.2017.00270.0         Access: Open Access Read More

Author(s): Vaseeha Banu T.S., Sandhya K.V., K.N. Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Manju Rawat, SJ Daharwal, Deependra Singh

DOI:         Access: Open Access Read More

Author(s): Saranya, Parthasarathy V, Hariprasad B, Shobha Rani H

DOI: 10.5958/0974-360X.2016.00233.X         Access: Open Access Read More

Author(s): Trophimus Gnanabagyan Jayakaran, Vignesh R, Shankar P

DOI: 10.5958/0974-360X.2019.00700.5         Access: Open Access Read More

Author(s): Barokar A.A., Wagh R.D., Baviskar D.T., Shaikh T.J.

DOI: Not Available         Access: Open Access Read More

Author(s): Ankita Chatterjee, Jayanthi Abraham

DOI: 10.5958/0974-360X.2016.00125.6         Access: Open Access Read More

Author(s): Y. Prem Kumar, K. Vinod Kumar, V. Sai Kishore

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags