Nikhat F, D Satynarayana, MG purohit
Nikhat F1*, D Satynarayana1 and MG purohit2
1Dept. of Pharm. Chem., Nitte Gulabi Shetty, Memorial, Institute of Pharmaceutical Sciences, Mangalore-574160
2Luqman College of Pharmacy, Old Jewargi Road, Gulbarga-585102 Karnataka India
Volume - 2,
Issue - 1,
Year - 2009
The object of this review is to highlight the therapeutic value of Syzygium cuminii (L) skeel belonging to the family myrtaceae. Several studies using modern technique has authenticated its use in diabetics and its complication (nephropathy, cataract, insulin resistance) using fruit pulp and leaves in combination or in pure form. The crude extracts are collected in succession by maceration with four solvents according to their increasing polarity of the solvent. The chloroform fraction of the total extract was loaded on the column and isolated seven constituents in higher quantity i.e. ScRex-1 (1.5g yield), ScRex-2, (1g yield), ScRex-3(1g yield), ScRex-4(1g yield), ScRex-5 (1.5g yield), ScRex-6a(2g yield), ScRex-6b(2.5g yield) . In our opinion the active constituent is obtained from the roots of Syzygyum cuminii (L) skeel are highly suitable for initiating hypoglycemic and antioxidant activity as evidence from our study which was carried out for short period (work we have published) it is possible that hypoglycemic and antioxidant activity will continued in a sustained manner over a longer period of time and there are innumerable possibility of incorporating the active ingredients in a suitable formulation.
Cite this article:
Nikhat F, D Satynarayana, MG purohit. Compiled Update on the Root’s of Syzygium cuminii (L) Skeel. Research J. Pharm. and Tech. 2(1): Jan.-Mar. 2009; Page 138-140.