Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Penetration Enhancement Techniques for Transdermal Drug Delivery System

Author(s): Vidyasagar Patidar, Dinesh Sharma, Deepika Maliwal, Vivekanand Chatap

Email(s): harm26@rediffmail.com

DOI: Not Available

Address: Vidyasagar Patidar*, Dinesh Sharma, Deepika Maliwal and Vivekanand Chatap
*B.R.Nahata College of Pharmacy (A SIRO and Innovation Network Partner under the Ministry of Science and technology, GOI), Mandsaur, (M P), India.
*Corresponding Author

Published In:   Volume - 2,      Issue - 1,     Year - 2009

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ABSTRACT:
It is remarkable fact that, in the new millennium Transdermal drug delivery system (TDDS) still account for more than 40% dosages forms administered to man. The principle reason for their continued popularity include their ease of manufacturer, their convenience of dosing and their stability compared with solid, liquid and semisolid presentation. TDDS delivery of drug through skin to the systemic circulation provides a convenient route of administration for a variety of clinical Indications. In TDDS wider range of drug is limited due to significant barrier to penetration across the skin, which is associated with outer most stratum cornium layer of epidermis. Various approaches are utilized for enhancement of penetration to bypass the stratum cornium such as optimisation of drug and vehicle properties, by stratum cornium modification, electrically based technique; Structure based technique and velocity-based technique. This review highlights physical and chemical parameters of various methods used in TDDS.


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Cite this article:
Vidyasagar Patidar, Dinesh Sharma, Deepika Maliwal, Vivekanand Chatap. Penetration Enhancement Techniques for Transdermal Drug Delivery System. Research J. Pharm. and Tech. 2(1): Jan.-Mar. 2009; Page 28-33.


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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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