Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Hepatoprotective activity of Momordicia diocia Roxb fruits in Carbon tetrachloride induced hepatotoxic Rats

Author(s): Prasannakumar BR, Mohammed Khallel, P Shankar

Email(s): pkumar_2005@rediffmail.com

DOI: Not Available

Address: Prasannakumar BR * Mohammed Khallel and P Shankar
Department of Pharmacology, MMU College of Pharmacy, Ramanagaram-571511
*Corresponding Author

Published In:   Volume - 2,      Issue - 1,     Year - 2009

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ABSTRACT:
The objective of this study was to evaluate the hepatoprotective activity of the fruits of Momordicia diocia by preparing different extracts and the resultant extract were screened for the hepatoprotective activity. The ethyl acetate and ethanolic extracts of Momordicia diocia fruits were prepared and subjected for phytochemical screening and tested for their hepatoprotective activity in carbon tetrachloride induced hepatotoxic rats. Phytochemical screening showed positive test for steroids, triterpenoids and glycosides (ethanolic extract). The ethyl acetate and ethanolic extracts have shown significant hepatoprotective activity at a dose of 200mg/kg.p.o. The study results suggested that Momordicia diocia fruits possess potential hepatoprotective activity.


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Cite this article:
Prasannakumar BR, Mohammed Khallel, P Shankar. Hepatoprotective activity of Momordicia diocia Roxb fruits in Carbon tetrachloride induced hepatotoxic Rats. Research J. Pharm. and Tech. 2(1): Jan.-Mar. 2009; Page 114-116.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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