Author(s): K. Anandakumar, K. Varadharajan, T. Ayyappan, P.Nageswara Rao, K. Sujatha

Email(s): anandkarunakaran@yahoo.com

DOI: Not Available

Address: K. Anandakumar*, K. Varadharajan, T. Ayyappan P.Nageswara Rao and K. Sujatha.
Dept. of Pharma. Analysis, Adhiparasakthi College of Pharmacy, Melmaruvathur -603 319 Kancheepuram (D.T), Tamil Nadu.
*Corresponding Author

Published In:   Volume - 1,      Issue - 4,     Year - 2008


ABSTRACT:
Three simple, precise and accurate UV-Visible spectrophotometric methods were developed for the estimation of Balsalazide in bulk drug and in pharmaceutical formulations. In method A, UV spectra of Balsalazide in double distilled water exhibits the absorption maxima at 358 nm. Method B is based on the formation of a dark red colored chromogen in alkaline medium at pH 12 exhibits ? max at 456 nm. Method C is the derivative spectroscopic method. The first derivative spectra were recorded between 200 and 500 nm at N=1 and the assay was carried out by measuring the absorbance at 383 nm. Beers law obeyed in the concentration range of 2-20 ?g/ml for methods A and B and 5-25 ?g/ml for method C. The accuracy of the method was determined by recovery studies. The method were validated statistically. The methods showed good reproducibility and recovery with % RSD less than 2. The methods were found to be simple, economical, accurate and reproducible and can be used for routine analysis of balsalazide in bulk drug and in pharmaceutical formulations.


Cite this article:
K. Anandakumar, K. Varadharajan, T. Ayyappan, P.Nageswara Rao, K. Sujatha. Estimation of Balsalazide in Bulk and in Formulation by UV-Visible Spectrophotometry. Research J. Pharm. and Tech. 1(4): Oct.-Dec. 2008; Page 472-474.


Recomonded Articles:

Author(s): Ravindranath S. Misal, Vishawas R. Potphode, Vijay R. Mahajan

DOI: 10.5958/0974-360X.2017.00218.9         Access: Open Access Read More

Author(s): Niharika, Navneet Verma

DOI: 10.5958/0974-360X.2016.00182.7         Access: Open Access Read More

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): Pankaj Kumar, Jane Jacob, Khadjeeth Ajina, Jazeela, Fathima

DOI: 10.5958/0974-360X.2016.00101.3         Access: Open Access Read More

Author(s): Narendra Chotai, Vishnu Patel, Harsha Patel, Uren Patel, Rajendra Kotadiya

DOI:         Access: Open Access Read More

Author(s): Archana Kushwaha, Jayanti Jaiswal, Priya Singh, Neha Rathore, Jai Prakash Dhruw, Ishu Sahu, Chhaya Singh, Krinsha Kumar Sahu, Mukta Agrawal, D. K. Tripathi, Ajazuddin, Amit Alexander

DOI: 10.5958/0974-360X.2017.00270.0         Access: Open Access Read More

Author(s): Homendra Kumar Sahu, Kamdev Sen, Raju Patel, Hulash Sahu, Deepika Sahu, Gulshan Sahu, Chandrashekhar Jain, Narayan Prasad Chandra, Mukta Agrawal, D. K. Tripathi, Ajazuddin, Amit Alexander

DOI: 10.5958/0974-360X.2017.00173.1         Access: Open Access Read More

Author(s): Hemlata M. Nimje, Rajesh J. Oswal, Sandip S. Kshirsagar, Manoj Chavan

DOI: Not Available         Access: Open Access Read More

Author(s): Vikram Kumar Sahu, Amit Mishra, Nitin Sharma, Pratap Kumar Sahu, Shubhini A. Saraf

DOI: 10.5958/0974-360X.2017.00048.8         Access: Open Access Read More

Author(s): Rao Rekha, Goswami Anju, Shekhar Shishant, Mahant Sheefali, Nanda Sanju

DOI: Not Available         Access: Open Access Read More

Author(s): H.B. Pagar, U.P. Shinde, Y.S. Agrawal, S.D. Barhate, T.S. Luhade, R.O. Sonawane

DOI: Not Available         Access: Open Access Read More

Author(s): Pratik N. Shah, Bhavini N. Patel, Chaganbhai N. Patel

DOI: Not Available         Access: Open Access Read More

Author(s): Rajendra Jangde, S. J. Daharwal

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags