Characterization of Ocular Delivery of Reverse Micelles Bearing Insulin

SK Jain; R Chandra; AK Rai

Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)

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Characterization of Ocular Delivery of Reverse Micelles Bearing Insulin

Author(s): SK Jain, R Chandra, AK Rai

Email(s): raivicte @ rediffmail.com

DOI: Not Available

Address: SK Jain3, R Chandra2 and AK Rai1*
1Pranveer Singh Institute of Technology Bhauti, Kalpi Road, Kanpur India
2Institute of Pharmacy Bundelkhand University, Jhansi-284128 (U.P) India
3Department of Pharmaceutical Sciences, Dr. H.S.Gour University, Sagar-470003 (M.P) India
*Corresponding Author

Published In: Volume - 1, Issue - 4, Year - 2008

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ABSTRACT:
Reverse micelle system bearing insulin was developed for controlled and prolonged release of drug through ocular route. The system was prepared by using cetyl tri-ammonium bromide and span-60 separately with organic solvent isopropyl myristate. The effect of temperature and polarity on the system was studied by measuring the drug content. In-vitro drug release study was carried out by using a Frang diffusion cell and artificial tear solution as diffusion medium. It was observed that the micellar systems exhibited prolonged and controlled release of insulin.

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Cite this article:
SK Jain, R Chandra, AK Rai. Characterization of Ocular Delivery of Reverse Micelles Bearing Insulin. Research J. Pharm. and Tech. 1(4): Oct.-Dec. 2008;Page 370-373.

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