Author(s): Wasim Raja, RC Agrawal, M Ovais

Email(s): wasimraja_84@yahoo.com

DOI: Not Available

Address: Wasim Raja1*, RC Agrawal1 and M Ovais2
1Department of Research, Jawaharlal Nehru Cancer Hospital and Research, Centre Idgah hills, BHOPAL (M.P.)
2Department of Biosciences, Barkatullah University Bhopal (M.P.)
* Corresponding Author

Published In:   Volume - 1,      Issue - 3,     Year - 2008


ABSTRACT:
In the present investigation, antimutagenicity of Lawsonia Inermis leaf extract was studied using a battery of mutagenicity test systems such us micronucleus and chromosomal aberrations in swiss albino mice. This plant is widely used as a cosmetic agent to stain hair, skin and nails. Three groups of Swiss albino mice were selected randomly (group with cyclophosphamide only, group with Lawsonia Inermis leaf extract plus cyclophosphamide and group with Lawsonia Inermis leaf extract only). A Single intraperitonial treatment of different concentrations (i.e. 500, 1000 and 1500 mg/kg body weight) dose of Lawsonia Inermis leaf extract was given along with the well known mutagenic agent to the experimental group. On comparing the outcome of all three groups, experimental and group with Lawsonia Inermis leaf extract showed significant reduction in micronucleus formation and chromosomal aberration in bone marrow cells after 24 hrs of administration. So it can be conclude that Lawsonia Inermis leaf extract can reduce the mutagenic potential of cyclophosphamide.


Cite this article:
Wasim Raja, RC Agrawal, M Ovais. Evaluation of Antimutagenocity Effect of Lawsonia inermis (henna) Leaf Extract in Swiss albino Mice. Research J. Pharm. and Tech. 1(3): July-Sept. 2008; Page 278-279.


Recomonded Articles:

Author(s): Nimbalkar V.V., Pansare P.M., Nishane B.B.

DOI: 10.5958/0974-360X.2015.00310.8         Access: Open Access Read More

Author(s): Raj Kumar R, Praveen D, Palani Shanmugasundaram

DOI: 10.5958/0974-360X.2016.00164.5         Access: Open Access Read More

Author(s): Siripurapu Sriram, Venkata Ravibabu Mandla, Chaithanya Sudha M, Saladi S.V. Subba Rao, Nagaveni Ch, Vani V., Gobinath P., Raj Kumar KVG., Jaydeep Lella, Sannidhi Krishna Praveen, Debjit Datta

DOI: 10.5958/0974-360X.2017.00078.6         Access: Open Access Read More

Author(s): M. Sumithra, Avantika Prabhabanik

DOI: 10.5958/0974-360X.2017.00036.1         Access: Open Access Read More

Author(s): Archana Kushwaha, Jayanti Jaiswal, Priya Singh, Neha Rathore, Jai Prakash Dhruw, Ishu Sahu, Chhaya Singh, Krinsha Kumar Sahu, Mukta Agrawal, D. K. Tripathi, Ajazuddin, Amit Alexander

DOI: 10.5958/0974-360X.2017.00270.0         Access: Open Access Read More

Author(s): Vaseeha Banu T.S., Sandhya K.V., K.N. Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Saranya, Parthasarathy V, Hariprasad B, Shobha Rani H

DOI: 10.5958/0974-360X.2016.00233.X         Access: Open Access Read More

Author(s): Ankita Chatterjee, Jayanthi Abraham

DOI: 10.5958/0974-360X.2016.00125.6         Access: Open Access Read More

Author(s): Barokar A.A., Wagh R.D., Baviskar D.T., Shaikh T.J.

DOI: Not Available         Access: Open Access Read More

Author(s): V Rajesh Babu, Syeda Rana Nikhat, P Nivethithai, SH Areefulla

DOI: Not Available         Access: Open Access Read More

Author(s): R. Suresh, D. Benitojohnson, C. Maheswari, R. Venkatnarayanan, R.Manavalan

DOI: 10.5958/0974-360X.2017.00128.7         Access: Open Access Read More

Author(s): Rao Rekha, Goswami Anju, Shekhar Shishant, Mahant Sheefali, Nanda Sanju

DOI: Not Available         Access: Open Access Read More

Author(s): Karthikeyan D, Vijayakumar S, Pandey V.P, Nandha Kumar J, Sengottuvelu S, T. Sivakumar T.

DOI:         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags