Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Synthesis and Analgesic Activity of Some Mannich Bases of 6-Substituted-2-Aminobenzothiazole.

Author(s): D. S. Bele, I. Singhvi

Email(s): indrajeetsinghvi@yahoo.com

DOI: Not Available

Address: D. S. Bele1 and I. Singhvi2
1B N Girls’ College of Pharmacy, Udaipur (Raj.) 313 001
2Pacific College of Pharmacy, Pratap Nagar, Airport Road, Udaipur (Raj) 313 003
* Corresponding Author

Published In:   Volume - 1,      Issue - 1,     Year - 2008

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ABSTRACT:
Mannich reaction between 6-substituted-2-aminobenzothiazole and 1-(5- substituted-1H-1,2,4-triazol-1-yl) ethanone in presence of formalin yield ten new mannich bases. All the synthesized compounds were characterized by UV, IR and 1H-NMR spectroscopy. The analgesic activity of the synthesized compounds was evaluated, on albino mice, by hot plate method using acetyl salicylic acid as reference standard. The present investigation results into compounds possessing good analgesic activity.


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Cite this article:
D. S. Bele, I. Singhvi. Synthesis and Analgesic Activity of Some Mannich Bases of 6-Substituted-2-Aminobenzothiazole.. Research J. Pharm. and Tech. 1(1): Jan.-Mar. 2008; Page 22-24.

Cite(Electronic):
D. S. Bele, I. Singhvi. Synthesis and Analgesic Activity of Some Mannich Bases of 6-Substituted-2-Aminobenzothiazole.. Research J. Pharm. and Tech. 1(1): Jan.-Mar. 2008; Page 22-24.   Available on: https://rjptonline.org/AbstractView.aspx?PID=2008-1-1-18


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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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