2nd International Conference on Fostering Interdisciplinary Research In Health Sciences (ICFIRHS) 2019 (01-May-2019)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   12

Issue No. :  8

Year :  2019

Pages :   3797-3801

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Effectiveness of Toothpaste containing Pyrophosphate and Papain to Inhibit Calculus Formation in patient using Fixed Orthodontic Appliance



Address:   I Gusti Aju Wahju Ardani1*, Monika Nilam2, Hana Arya Puspita2, Ida Bagus Narmada1
1Orthodontic Department, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
2Undergraduate Student, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
*Corresponding Author
DOI No: 10.5958/0974-360X.2019.00650.4

ABSTRACT:
Patients using fixed orthodontic appliance are more susceptible to calculus formation than patient without orthodontic treatment. Pyrophosphate and papain toothpaste can be used to reduce dental plaque and calculus accumulation. The aim of this study was to analyze the differences in the calcium level and phosphate level in saliva, also saliva pH in patient’s after treated with toothpaste containing pyrophosphate and papain. This study was true experimental study with pre-test and post-test controls group design with random sampling. Sample size was (n=20). Sample was 17-22 years old male or female patient using fixed orthodontic appliance. Sample divided into two groups: control group treated with placebo toothpaste and treatment group treated with toothpaste containing pyrophosphate and papain with blind method. Patients were instructed to brush their tooth twice a day daily. 3 ml unstimulated saliva was collected on the Day 1, 3, and 5. Spectrophotometer Atom Absorbance (SAA) was used to measure calcium level and phosphate level in saliva, while saliva pH measurement using pH meters. Treatment group showed lowest mean (SD) calcium level [1.12(0.29]. Calcium level in treatment group between groups (p<0.05) was significantly different. Saliva pH was insignificantly different between groups (p>0.05). Treatment group showed lowest phosphate level in Day 5. Phosphate level in treatment group between groups (p<0.05) was significantly different. Toothpastes containing pyrophosphate and papain decreased calcium levels, phosphate levels effectively and maintaining normal salivary pH to inhibit calculus formation in patients using fixed orthodontic appliance.
KEYWORDS:
Calcium level, Phosphate level, Pyrophosphate, Papain, saliva pH.
Cite:
I Gusti Aju Wahju Ardani, Monika Nilam, Hana Arya Puspita, Ida Bagus Narmada. Effectiveness of Toothpaste containing Pyrophosphate and Papain to Inhibit Calculus Formation in patient using Fixed Orthodontic Appliance. Research J. Pharm. and Tech 2019; 12(8): 3797-3801.
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