Brain Tumor Segmentation using Contextual Clustering and Object Labeling in MRI

 

G. Merlin Sheeba*, M. S. Godwin Premi, G. Mary Valantina, Z. Mary Livinsa

School of Electrical and Electronics, Sathyabama Institute of Science and Technology, Chennai

*Corresponding Author E-mail: merlinsheebu@gmail.com

 

ABSTRACT:

Brain tumor segmentation in MRI images is one of the challenging tasks in medical field. In this work, an efficient brain tumor is detection methodology is proposed for the MRI images. Image preprocessing filters are used to remove noises from the images. Contextual clustering extracts the tumor regions from the images Object labeling is also performed following the contextual clustering. The simulation results show that the proposed technique has achieved 94% of efficiency.

 

KEYWORDS: Contextual clustering, object labeling, Segmentation.

 

 

 

INTRODUCTION:

Brain tumor is occurred when abnormal cells are formed with in the brain.  Malignant and Benign are the two main types of tumor. These tumors cause headache, vision problems, vomiting, and also some mental changes. As the disease progresses unconsciousness also may occur. This is the risk factor which the doctors are unable to operate it with confidently. The success of medical imaging system depends on proper segmentation of the images.

 

The major challenge in analyzing MRI brain images is to classify the pixels of images into homogeneous regions. This type of problems is termed as clustering or segmentation problem. Segmentation is the process of dividing the image into multiple segments. The goal of the segmentation is to simplify or change the representation of the image into something easier to analysis. There are many segmentation methods are followed, such as, compression based method, histogram based method, region growing method, edge detection method, split and merge method, etc. This project depends about the clustering.

 

Clustering deals with finding a structure in a collection of unlabelled data. A clustering is a process of the objects is made into groups whose members are similar in some way. A collection of object which is similar and as similar in between them is called as cluster. The segmentation of the human brain image from the MRI (magnetic resonance imaging) is made into three different tissues. They are cerebrospinal fluid, gray matter and white matter. Fuzzy c-means clustering is widely (FCM) used for image segmentation. But the FCM clustering are not accurate in dealing with local spatial property of images which leads to strong noise sensibility. In most of the medical images are not proper and also some unknown noise will leads to degrade in segmentation quality. For this purpose we are making use of this contextual clustering to get a clear view of the brain tumor. Our method is to detect the object (MRI images) to give a clear quality for the operation purposes.

 

RELATED WORKS:

M. Mohammed and D.B. Mohammed [1] presented to produce the segmentation of the brain MRI images for the extraction by using the K-means clustering and Perona-Malik anisotropic diffusion model. Segmentation by manually of these abnormal tissues cannot be compared now which enable us to observe the volume and location of unwanted tissues. The segmentation of the brain will be divided according to their tissue type which includes White Matter (WM), Gray Matter (GM) and Cerebrospinal Fluid (CSF). These tissues are not properly shown .In this method T1,T2 and PD weighted gray level intensity images are used. J. Selvakumar et .al [2] have performed the Brain tumor segmentation by using k-means clustering and fuzzy c-mean algorithm (FCM). They have implemented FCM Algorithm for detection of the range and shape of tumor in brain MRI images. Uncontrolled growth of tissues in any part of the body is called as tumor.  As it is known, brain tumor is inherently serious and life-threatening because of its character in the short space formed inside the skull. The scans or MRI that is directed into the cavity produces a complete image of brain. This image of tumor is examined by the physician and made to be detected. This method of detects the stage and size of tumor. To avoid that, this project uses the segmentation of brain tumor based on the combination of both algorithms. In addition, it also reduces the time in analyzing. The tumor is taken from the MRI image and its actual position and shape is determined. The Brain MRI segmentation for tumor detection is done by cohesion based self merging algorithm (CSM) was explained by S. Koley et .al [3] deals with the segmentation of brain MRI for determining the exact location of brain tumor by CSM with partitioned K- means clustering algorithm. The CSM is made to be compared and the noise is also made to be reduced. This method is much simpler and computationally less complex and computation time is also less. M. Shasidhar et. al [4] have recommended the MRI brain image segmentation using modified fuzzy c-means clustering (FCM) algorithm. In this process the Clustering approach is widely used in biomedical applications especially for brain tumor detection in MRI images. Fuzzy clustering using fuzzy C-means (FCM) algorithm is superior over the other clustering approaches in terms of segmentation efficiency. The effectiveness of the FCM algorithm rate is improved by modifying the cluster center and membership value updating criterion. In this method, the FCM algorithm for MR brain tumor detection is explored. Comparative analysis in terms of efficient segmentation and the convergence rate is performed between the conventional FCM and the modified FCM. This process show superior results for the modified FCM algorithm in terms of the performance measures. For the brain tumor pattern image processing technique is used which was presented by Kimmi Verma et .al [5].  The research was done which made by the use of software with edge detection and segmentation methods, which gave the edge pattern and segment of brain and brain tumor itself. Medical image will play a vital point in research, as it is complex problems for the proper diagnosis of brain disorders. In this research, it is a foundation of segmentation and edge detection, as the first step towards brain tumor grading. The segmentation is reviewed with an emphasis placed on revealing the advantages and drawbacks of these methods for medical imaging applications.

 

MATERIAL AND METHODS:

System Description:

The block diagram of the proposed method is shown in figure 1.Intially the MRIimage is  preprocessed wherein the filtering techniques are used.

 

The MRI brain tumor image is given as the input of  the proposed system. As shown in the figure 1, the image preprocessed is the first step in this process. The conversion of the image from RGB to grayscale image is done.While in the conversion process there may be some kind of noise might be added in the image .Even though the  image is in good quality the noise should be added in the  process. The image is added with 0.05% of salt and pepper noise. Now the image will be a noisy image and this noise will be removed by the median filter .These  are the preprocessed methods in the given image. The salt and pepper noise are removed by the Median filter.

 

Morphological Operations on Binary Images:

The Morphological operations will affect the form, structure or shape of an object. After the median filter the process of morphological opening is done as shown in the fig.1.Here in this process the Erosion and Dilation is done. The morphological opening is first done with Erosion and then only with Dilation. But in the morphological closing method the process of Dilation is done first then only with Erosion. The range of the grayscale image is 0-255.

 

Erosion:

The erosion is process of eroding the image ,it turns the black to white pixel. The structuring element is made to be done with erosion process. The pixels will be altered by this process. The outer part of the mri images are eroded in this process. The erosion will make the image more clear for the doctor purpose. As shown in the fig.2. the tumor part will be clearly distinguished in this method. After this process is done then the image is made to be diluted.

 

 

 

Dilation:

The dilation process is performed by laying the structuring element on the image. After the erosion phase is completed the  image is diluted. This will be done in the inner part of the tumor, hence a clear view of the tumor is possible. The dilution is just the opposite of the erosion process. This two process will make the image to be complete in the morphological opening process as shown in figure 2.

 

Contextual Clustering:

The recognition of the active region is the process of contextual clustering. According to the statistical property the activation class is unknown and the background class is known. A testing of hypothesis is used to deal with this kind of classification problem. In the present case, the null hypothesis is that the pixel under consideration is zero from the background class. In a standard one-tailed test of a null hypothesis, the zero hypothesis would be rejected, and if the statistical value are smaller than zero.

 

In order to develop a contextual testing method, a hypothetical activation class, or rejection class, is defined. The class determines a difficult region corresponding to an “different event”. Pixels whose characteristics are “closer” to the rejection class than the background class violate the null hypothesis and are put into the rejection class and considered active [6,7]. The standard normal distribution is obtained by the background class. Suppose that there is no contextual support toward either accepting or rejecting the null hypothesis. The null hypothesis is rejected in this conventional hypothesis because the pixel value is smaller than a user specified threshold.  It is assumed, therefore, that the rejection class follows a distribution, which guarantees that the rejection probability will be a single increased function. The definition of the rejection class is required to formulate the testing problem as a classification problem. The detection problem is now reduced to a two class-segmentation problem [8] that can be solved using standard methods. The cluster variation is shown in Figure 3.

 

Object Labeling:

The main motive of this project to detect the tumor from the brain. So the object labeling algorithm is used to detect accurate part of brain tumor. Object Labeling is the process of labeling the given image. Here in this process the MRI image are labeled. The binary image of the tumor will be labeled accordingly. The simulation results are compared different tumors in Table 1.

 

 

TABLE 1: Experimental results

MRI Images

Types of Tumor

MSE

PSNR

 

Maligant

13.2955

36.9277

 

Benign

8.0933

39.0836

 

Benign

27.591

33.7571

 

CONCLUSION:

The main contribution of the work is to explore various techniques to detect brain tumor in an efficient way. This work has proposed a new object based brain tumor detection along with the decision based median filtering. The design and implementation of the object labeling algorithm is done in MATLAB using GUI (graphical user interface). The experimental results of the proposed technique has achieved up to 94% accuracy. This method can detect tumor in high noisy images as well.

 

REFERENCES:

1.      Revathy, M. (2012). Image classification with application to MRI brain using 2nd order moment based algorithm. International Journal of Engineering Research and Applications (IJERA), 2(3), 1821-1824.

2.      Sucharita, V., Rao, P. V., Bhattacharyya, D., and Kim, T. H. (2016). Classification of Penaeid Prawn Species using Radial basis Probabilistic Neural Networks and Support Vector Machines. International Journal of Bio-Science and Bio-Technology, 8(1), 255-262.

3.      Padma, A., and Sukanesh, D. R. (2011). Automatic diagnosis of abnormal tumor region from brain computed tomography images using wavelet based statistical texture features. arXiv Preprint arXiv:1109.1067.

4.      De Boer, R., Van Der Lijn, F., Vrooman, H. A., Vernooij, M. W., Ikram, M. A., Breteler, M. M., and Niessen, W. J. (2007, April). Automatic Segmentation of Brain Tissue and White matter Lesions In MRI. In 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro (pp. 652-655). IEEE.

5.      Anbeek, P., Vincken, K. L., and Viergever, M. A. (2008). Automated MS-lesion segmentation by k-nearest neighbor classification. MIDAS Journal.

6.      Qurat-Ul-Ain, G. L., Kazmi, S. B., Jaffar, M. A., and Mirza, A. M. (2010). Classification and segmentation of brain tumor using texture analysis. Recent advances in artificial intelligence, Knowledge Engineering and Data Bases, 147-155.

7.      Mancas, M., Gosselin, B., and Macq, B. (2006, January). Tumor detection using airways asymmetry. In 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference (pp. 6528-6531). IEEE.

8.       Sheeba, G. M., and Memala, A. (2018, May). Detection of Gaze Direction for Human–Computer Interaction. In International Conference on ISMAC in Computational Vision and Bio-Engineering (pp. 1793-1803). Springer, Cham.

 

 

 

 

Received on 21.06.2019         Modified on 09.09.2019

Accepted on 29.10.2019         © RJPT All right reserved

Research J. Pharm. and Tech. 2020; 13(4):1833-1836.

DOI: 10.5958/0974-360X.2020.00330.3