A Prospective Study on Quality of Life in Menorrhagia Patients with Anemia
Dr. T. S. Shanmuga Rajan1, S. Yeswanthi2
1Associate Professor, Department of Pharmaceutics, VISTAS, Vels University, Pallavaram, Chennai, India.
2School of Pharmaceutical Sciences, VISTAS, Vels University, Pallavaram, Chennai, India
*Corresponding author E-mail: shanmuga5@velsuniv.org
ABSTRACT:
BACK GROUND: Menorrhagia is heavy menstrual bleeding which causes anemia due to heavy blood loss i.e., more than 80ml. The purpose of this study is how did menorrhagia effects on women’s quality of life. The main aim of the study is to assess the quality of life in menorrhagia with anemia.
METHODS AND MATERIALS: A total of 100 patients were included in the study with heavy menstrual bleeding. The PCS and MCS scoring were done by using SF-12 questionnarie. The statistics were done by using student t test.
RESULTS: The age group of 26-35 (41%) and 77% of married people were mostly affected. The haemoglobin level of menorrhagia patients were found to < 12g/dl. The PCS and MCS scoring before and after counselling are 39.6±4.12, 51.2±3.66(PCS), 34.7±1.16, 49.6±2.19 (MCS) respectively. The P value is <0.05* and <0.01** is calculate by using student t test. The PCS and MCS were significantly increased after counselling.
CONCLUSION: Menorrhagia with anemia has negative effect on women’s quality of life. Hence, the study concludes that quality of life was improved on anemia in menorrhagia patient’s after counselling. We recommended for the further research study should focus on abnormalities in menorrhagia patients, for the effective treatment and better patient compliance.
KEYWORDS: quality of life, physical component scoring, mental component scoring.
INTRODUCTION:
Menorrhagia is defined as heavy menstrual bleeding which may last more than 7 days. It can cause menstrual bleeding of more than 80ml in each cycle.1 Heavy menstrual bleeding (HMB) is a common problem among women of reproductive age and has a major impact on a woman’s quality of life, disturbing physical activity and work performance as well as social and emotional life2 .
The causes of menorrhagia in gynecological and endocrinological conditions in terms of organic pathology (primarily fibroids) and anovulation/hormonal imbalance, with remaining etiologies being systemic disorders such as hypothyroidism and iatrogenic causes including intrauterine devices and use of anticoagulants3.
Menorrhagia is largely responsible for anemia and also iron deficiency anemia. Both of which have negative effects on women’s quality of life. Heavy menstrual bleeding is the common cause for the iron deficiency anemia. Mostly women of age 25-40 were mostly effected with menorrhagia4.
Menorrhagia patients mostly have pain and discomfort, which effects health related quality of life in women5. Anemia is the major cause in patients with heavy menstrual bleeding due to heavy blood loss i.e., more than 80ml 6.
Anemia is defined as the lack of red blood cells or haemoglobin. Haemoglobin is a main part of red blood cells and binds oxygen. The causes for this mostly are heavy menstrual bleeding, decreased red blood cell production 7.
Quality of life is the perceived quality of life on individual’s daily life , which includes emotions, aim, social and physical aspects8 . In many studies it shows that menorrhagia has negative effects on women’s quality of life 9.
The aim of the study was to assess women’s quality of life in menorrhagia with anemia using SF-12 questionnaire.
MATERIALS AND METHODS:
SAMPLE SIZE: 100 patients
INCLUSION CRITERIA:
• Female patients of 18-45 years of age
• Patients who diagnosed with menorrhagia
EXCLUSION CRITERIA:
• Patients below 18 years and above 45 years of age.
• Patients who underwent hysterectomy and bilateral oophorectomy.
• Pregnancy and lactating women.
STUDY DESIGN:
A prospective study
STUDY INSTRUMENT: SF 12 questionnaire
DURATION: 12 months
It is a prospective study. The women patients who are having complaints of menorrhagia were included in the study. The information is collected like patients name, age family history, past medical history. The data was collected directly i.e., via face to face with SF-12 questionnaire. The questionnaire forms consist regarding physical health and mental health. The study was conducted after obtaining informed consent form from the patient. The study was approved by the ethics committee IEC/DOPV/2015/2016.
RESULTS:
The following results were obtained when the data collected.
Table 1: Distribution based on Age
|
Age |
No. Of patients |
Percentage |
|
18-25 |
29 |
29% |
|
26-35 |
41 |
41% |
|
36-45 |
30 |
30% |
Table 1 shows that age group 26-35 were mostly affected with menorrhagia.
Table 2 : Distribution based on BMI
|
BMI |
No. Of patients |
Percentage |
|
<18 |
21 |
21% |
|
19-25 |
57 |
57% |
|
>25 |
32 |
32% |
Table 2 shows that people with menorrhagia there will be changes in BMI.
Table 3: Distribution based on Marital status
|
Marital status |
No.of patients |
Percentage |
|
Un married |
23 |
23% |
|
Married |
77 |
77% |
Table 3 shows that 77% of married people affected with menorrhagia.
Table 4: Distribution based on partum status
|
Partum status |
No. Of patients |
Percentage |
|
Pre partum |
37 |
37% |
|
Post partum |
63 |
63% |
Table 4 shows that 63% post partum people were affected with menorrhagia.
Table 5: Distribution based on anemic status
|
Hb level |
No.of patients |
Percentage |
|
<7g/dl |
39 |
39% |
|
7-9 g/dl |
21 |
21% |
|
9-12 g/dl |
40 |
40% |
Table 5 shows that people are mostly having anemia due to heavy menstrual bleeding.
Table 6: PCS and MCS before and after counselling
|
|
Before counselling |
After counselling |
P value |
|
PCS |
39.6±4.12 |
51.2±3.66 |
<0.05* |
|
MCS |
34.7±1.16 |
49.6±2.19 |
<0.01** |
Table 6 shows that PCS and MCS were improved significantly improved after counselling.
Table 7: Comparison of PCS and MCS in pre partum and post partum
|
|
|
Before counselling |
After counselling |
P value |
|
|
Pre partum |
39.16±2.16 |
52.32±4.14 |
<0.05* |
|
PCS |
Post partum |
37.10±3.14 |
49.16±3.73 |
<0.01** |
|
|
P value |
>0.05 |
>0.05 |
|
|
|
Pre partum |
33.36±4.11 |
47.46±4.21 |
<0.05* |
|
MCS |
Post partum |
38.40±3.12 |
51.32±3.16 |
<0.01** |
|
|
P value |
>0.05 |
>0.05 |
|
Table 7 shows that PCS and MCS were significantly improved after counseling.
DISCUSSION:
Sule Gokylidiz et al shows that Menorrhagia is considered to be one of the most significant causes of ill health in women. One in 20 women aged between 30 and 49 years consults her general practitioner each year with heavy menstrual loss.
Sergio simoes de souse et al shows that Hemoglobin and QoL showed significant improvement after treatment (p < 0.001). Hemoglobin level was the only independent predictor of the QoL measured by SF-36 physical (p = 0.03) and mental (p = 0.04) composites scores. The impact on the QoL was associated with the hematimetric parameters.
Pirkko peuranpaa et al shows that after treatment of HMB, HRQoL increased more in initially anemic than in nonanemic women, indicating that the increase of HRQoL is linked to correction of anemia.
Our study shows that age group of 26-35 were mostly affected. Married people are mostly affected with menorrhagia.
In this study it indicates that people with menorrhagia are mostly having anemia (table 7). Anemia is caused due to heavy blood loss.
The PCS and MCS were calculated by SF-12 scoring. This is calculated by using student t test.
These are improved significantly after counseling.
CONCLUSION:
Menorrhagia has negative effects on women’s quality of life. Therefore, quality of life of the women consulting the clinics with menorrhagia complaint should be investigated and effective approaches should be designed accordingly.
The physical and mental component summaries showed statically significant difference determined by student t test.
Hence, the study concludes that quality of life was improved on anemia in menorrhagia patient’s after counselling.
We recommended for the further research study should focus on abnormalities in menorrhagia patients, for the effective treatment and better patient compliance.
ACKNOWLEDGEMENT:
The authors are grateful to the management of Vels Institute of Science Technology and Advanced Studies (VISTAS).
REFERENCE:
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Received on 27.04.2017 Modified on 24.05.2017
Accepted on 31.05.2017 © RJPT All right reserved
Research J. Pharm. and Tech. 2017; 10(7): 2233-2235.
DOI: 10.5958/0974-360X.2017.00395.X