Medicinal Aspects of Saccharum munja

 

Rahar Sandeep 1, Nagpal Navneet1, Swami Gaurav 2, Arora Manisha1, Bansal Suraj3,  Goyal Sandeep3, Singla Shwali4, Singh Preeti5 and Kapoor Reni6

1B.I.S.College of Pharmacy, Moga, India.    2CT Institute of Pharmaceutical Sciences, Jalandhar, India 3S.D.College of Pharmacy, Barnala, India 4Geetanjali Institute of Pharmacy, Udaipur, India      5Saroj Institute of Management and Technology, Lucknow, India6Akal College of Pharmacy, Sangroor, India

*Corresponding Author E-mail: rahar_s@yahoo.co.in

 

ABSTRACT:

Saccharum munja was traditionally used in making ropes and baskets. It is one of the best nutritious and drought tolerant species of grasses. A valuable fiber can be extracted from upper leaf sheets of flowering culms. The stem is sweet, acrid, cooling, aphrodisiac and is useful in burning sensations, thirst, erysipelas, blood troubles, urinary complaints, eye diseases and tridosha. The plant stem, flowers and adjacent soil found to have nutrients such as sodium, potassium, calcium, magnesium, iron, chlorides, bicarbonates, sulphates and phosphates which are responsible for its medicinal importance. The plant parts are used in number of Ayurvedic formulations which are used in the treatment of dysuria.

 

KEYWORDS: Saccharum munja, nutrients, dysuria, soil.

 


INTRODUCTION:1-5

Saccharum munja, known as munja is a grass found in arid areas and along river banks in India. The grass is tall, panicles silky and greenish brown. The grass grows in excess and up to 7 feet in height. Leaf sheath shortly silky at extreme base, otherwise quite smooth, straite, pale straw colored, villous on margins at apex with long white hairs usually much longer than proper internode, uppermost sheath sometimes extending beyond the base of panicle. Its white flowers are of ornamental value. The common name of the plant is Kana or Sarkanda or Moonja and is distributed from north and North West India to Pakistan and Afghanistan. There are 24 vernacular names of plant in Sanskrit language such as bahupraja, bana, bhadramunja, brahmanya, chakshuveshtana, darbhavhaya, dridhatrina, durmula, ikshukanda, maunji, munja, munjanaka, munjata, ranjana, sara, shakrabhanga, shara, shiri, sthuladarbha, sumekhala, tejana, tejanavhaya, trinakhaya, vaniraka. Flowering and fruiting are perennial and mostly from October to January. The plant is a large tufted grass and is of little account as fodder plant because cattle and buffaloes eat young leaves only during scarcity of food. The stem is used in making chiks and moorhas.

 

The flowering scape is woven into winnowing trays (Chhaj) and cover for grain heaps and carts, while the thick sheath next to scape is twisted into strings for weaving bed-streads etc.

 

Nutritive Elements in Saccharum munja:6-19

Plants possessing their antibiotics properties have been well known since old civilization of Romans, Egyptians and Arabs. The plant barks, leaves, roots, juices, gums, fruits and seeds in heterogenous ground mixture or in solution form are used in the treatment of several diseases. Keeping in view the medicinal importance of Saccharum munja, inorganic nutrients were determined from its stem, flowers and adjacent soils.

 

Figure 1: Saccharum munja

Table 1: Classification

Kingdom/Regno

Planate (Plants/Piante)

Subkingdom/Sottoregno

Tracheobionta (Vascular plants/Piante Vascolari)

Superdivision/Superdivisione

Spermatophyta (Seed plants/Piante con Semi

Division/Divisione

Magnoliophyta (Flowering plants/Piante  Con fiori)

Class/Classe

Liliopsida(Monocotyledons/Monocotiledoni)

Subclass/Sottoclasse

Commelinidae

Order/Ordine

Cyperales

Family/Famiglia

Poaceae (Grass family)

Genus/Genere

SaccharumL. (sugarcane)

Species/Specie

Munja/Bengalense/Sara

 

Table 3 shows that the sodium level in stem (5-10 ppm) is lower than the flower (10-40 ppm), while 10 ppm in their soils. Level of pottassium in stem (40.8-70.9) is higher compared to the level in flowers (0.4-10.4 ppm) 0f the plant and the soils (10-35 ppm). Sodium and Potassium cations perform various electrochemical functions in the human body such as emulsion stabilization, charge neutralization and supply of free energy during cell stimulation. During muscle contraction and nerve stimulation Na+ enters and Ka+ leaves the cell the potential difference across the cell membrane changes temporarily. The ATP (Adenosine triphosphate), the metabolic energy is then needed to pump Ka+ back and Na+ out for normal condition. Na+ and Ka+ stabilize the oil in water emulsion and maintain the solubility of proteins as globulin is insoluble in water but soluble in dilute salt solutions.

 

The plant stem (24-80 ppm) and flowers (24-120 ppm) has higher levels of calcium as compare to soil (0.14-6 ppm) in which Saccharum munja is planted. Calcium plays an important role as factor IV in blood clotting mechanism. Calcium alongwith thromboplastin is required to convert prothrombin to thrombin, which activate fibrinogen to fibrin network.

 

The level of magnesium in plant stem (43-430 ppm) and flowers (0.48-48 ppm) is higher than its level in soil (0.21-1.26 ppm). Magnesium plays an important role in the activation of enzymes which transfer phosphate from adenosine triphosphate to adenosine triphosphate which are fundamental and widespread and thus influence all basic life processes such as glycolysis. The physical stability of DNA, chromosomes and ribosomes is also depends on magnesium. Therefore a certain amount of magnesium is required for cell duplication. However there is no deficiency of Mg+2 in the body but during renal failure and alcoholism magnesium deficiency may be there which may cause muscular tremor, hallucination, depression and spasmophilia. Excess amount of magnesium may cause neuromuscular tranmission blockage.

 

High level of iron (172-860ppm) is present in soil as compared with plant stem (285-704) and plant flowers (218-553). The human body contains 4-6 gm of Fe out of which 1 gm is present in liver and spleen. Iron is present in body as a component of haemoglobin and myoglobin and responsible for oxygen transport and cell respiration.Iron is also present in intracellular cytoshrome enzyme system, which is responsible for energy production.During pregnancy the high intake of iron is required due to iron deficiency. The daily requirement of iron is 10-20 mg if not maintain the deficiency will be there which may lead to hemolytic anemia, stomatitis, listlessness, palpitation, excretion and slow physical activity. The extra intake of iron (above 50 mg) accumulates in the liver in the form of haemosidrin and lead to haemachromatosis having symptoms of gray, skin pigmentation, hepatic enlargement, pancreatic infilteration with diabetes and myocardial diseases leads to heart failure.

 

Chlorides found in stem (157-203ppm) and a flower (199-500ppm) is higher than the soil (17.8-78ppm). Chloride is absorbed from the soil in the form of chloride ions (Cl-1) without becoming a structural unit and is essential for water balance, regulation in osmotic pressure and acid base equilibrium. It may be used in cell division in roots and leaves.

 

Bicarbonates in stem (300-710ppm) and flowers (288-820ppm) as compared to soil (106-600ppm). Pancreatic secretion consists of an aqueous bicarbonate component from the duct cells and enzymatic component from the acinar cells and is alkaline in nature due to the high concentration of bicarbonate ions. This is useful in neutralizing the acidic gastric acid, allowing for effective enzyme action. Bicarbonate/chloride (HCOGraphic-1/Cl-1) exchangers regulate intracellular pH in the alkaline range.

 

Phosphate ions in stem (0.7-1.04ppm) and flowers (0.35-0.8ppm) is higher than soil (0.1-0.25ppm). Phosphater is used in transport of fatty acids within the cell. It is also used in storage and transfer of metabolic energy through phosphate bonds such as adenosine triphosphate (ATP) and adenosine diphosphate (ADP).

 

Sulphate ions lower in plant stem (86-154ppm) and plant flowers (20-240ppm) as compared to adjacent soil (100-250ppm). Sulphur is also responsible for high energy bond formation as in acetyl coenzyme-A and in derivative of lipoic acid (thioctic acid). The sulphahudryl group (-SH) binds with heavy metals by acting as chelating agent and is used in detoxification mechanism. The example of detoxication agent is “British antileiwisite” which act by binding the arsenic atoms in chlorovinylarsine poison gas. Similarly B-penicillamine act as detoxification agent in lead poisoining.

 

Organic Constituents1

Stem yields 5.67% of furfural on dry basis.It also yields 19.5% of reducing sugars like glucose, xylose, galactose and rhamnose when digested with sulphuric acid. The hydrolysate contains about 34.5% of fermentable sugars.

 

 


Table 2: Synonyms and Species

Synonyms

Species/Specie

Sanskrit

Bhadra, Munja

Saccharum alopecuroides

Saccharum japonicum

Bengali

Sara

Saccharum alopecuroideum

Saccharum kanashiroi

Gujrati

Sarkat

Saccharum angustifolium

Saccharum koenigii

Hindi

Sarkand, Munja

Saccharum arenicola

Saccharum longisetosum

Kannad

Munji,Hullu, Hodake Hullu

Saccharum arundinaceum

Saccharum munja

Malayalam

Ama,Amaveru, Sara, Munjapullu

Saccharum asperum

Saccharum munroanum

Marathi

Munja,Trikande, mole

Saccharum balansae

Saccharum narenga

Orrisa

Sara

Saccharum barberi

Saccharum officinarum

Punjabi

Moonja, Sarkanda

Saccharum beccarii

Saccharum paniceum

Tamil

Munjipul, Munjapullu

Saccharum biflorum

Saccharum pappiferum

Telugu

Gundra, ponica

Saccharum brevibarbe

Saccharum perrieri

Tibetan

Dambu

Saccharum ciliare

Saccharum procerum

Urdu

Munja, Sarkanda

 

 

 

Table 3: Comparison of Nutrients in Saccharum munja

Sample

Sample Type

 

pH

Moisture %

 

Organic Contents %

Soluble Salts

%

Na+

PPm

 

k+

PPm

 

Ca+2

PPm

 

Mg+2

PPm

 

Fe+3

PPm

 

Cl-1

PPm

 

HCo3-1

PPm

 

PO4-2

PPm

 

SO­­­4-2

PPm

 

A

Soil

Stem

Flower

7.78

-

-

7.14

-

-

4.48

-

-

15.38

-

-

10.05

10

10

35

40.8

0.4

6.0

40

32

1.2

430

31.2

860

285

218

17.8

178

199

410

490

820

0.13

1.04

0.35

100

86

20

B

Soil

Stem

Flower

7.60

-

-

3.45

-

-

7.40

-

-

10.29

-

-

10.20

5

15

10.15

70.9

10.3

0.27

80

24

0.21

140

28.8

229

569

553

78.4

157

500

106

710

288

0.2

1.0

0.8

200

154

240

C

Soil

Stem

Flower

7.30

-

-

13.63

-

-

3.93

-

-

14.50

-

-

10.00

5

40

10.00

60.1

10.4

0.14

24

120

1.26

43

48

172

704

540

71.2

203

311

600

300

600

0.25

0.7

0.35

250

154

48

(Average value, n = 4, Confidence interval at 95%)

 

Table 4: Ayurvedic Formulations

Sr. no.

Formulation

Active Ingredients

Therapeutic Uses

1

Ashmari Kalp

Ashmari Kalp is an ayurvedic formulation for Urogential system care.

Kus (Desmostachya bipinnata)

Kas (Saccharum spontaneum)

Sar (Saccharum munja)

Darbh(Imperata cylindrica)

Sikhs (Saccarum officinarum)

Sahijan(Moringa oliefera)

Varun(Crataeva vanurvala)

Removes burnings

painful micturition, irregular, frequent micturition. It is also useful in renal calculi, dysurea etc.

 

2

Neeri

A perfect polyherbal regime, developed and formulated on the scientific concept, which exerts overall therapeutic activity with safety in various types of urinary disorders like urinary calculi (kidney stone), urinary tract infections and prostate associated disorders. Neeri is an experimented, documented and clinically proven herbal regime to treat both the causes and effects in urinary disorders.

 

 

 

Sudh Shilajeet (asphaltum)

Swait Parpati (AFI)

Moolishar L.(Raphanus sativus)

Sheetal Chini (Piper cubeba )

Saindha Namak (Rock Salt)

Sajjikhar( Soda bicarbonate)

Punernava Boerhaavia diffusa

Panchtrin Mool (ASS)

Ikshu (Saccharum officinarium)

Gokshru (Tribulus terrestris)

Chharilla (Parmelia periata}

Varun (Crataeva nurvala)

Kulatha (Dolichos biflorus)

Pashan (Bhed Bergenia ligulata)

Palashpushp(Butea monosperma)

Lajaloomool (Mimosa pudica)

Makoi (Solanum nigrum)

Kakri Beej (Cucumis sativus)

Daruharidra (Berberis aristata)

Panchtrin Mool (ASS)

Kush (Desmostachya bipinnata)

Kass (Saccharum spontaneum)

Sarr (Saccharum munja)

Darbh (Eragrostis cynosuroides)

Ikshu (Saccharum officinarium)

(All are in equal quantities)

Resolves and dissolves urinary stones and urinary Infections

 

3

Trnapancamula Kvatha Curna

Saccharum munja

Useful in burning sensations, thrist and dysuria.

4

Brahma Rasayana

Saccharum munja

Used in painful micturations and urinary complaints.

5

Sukumara Ghrta

Saccharum munja

It is used as diuretic cooling and removes painful micturations.

 


Therapeutic uses1, 3, 20-26

·        Saccharun munja is used as Refrigerant.

·        Saccharum munja is useful in burning sensation, thrist, herpes, duypepsia, dyscaria, erysipelas and urinary complaints and diseases of eyes.

·        Roots of Saccharum munja used in dysuria, giddiness and vertigo.

·        Saccharum munja is used to cure bleeding wounds.

·        Roots of Saccharum munja also used against fever and inflammation.

·        Saccharunm munja grass as a type of gauze-pad to stop blood flow.

·        The smoke of roots burnt near women after delivery and burns scalds.

 

According to ayurveda Saccharum munja has following properties:

Aksiroga,Bastisula,Bhrama,Daha,Guna,Karma,Mutrakrcchra,Murcha,Rasa,Trsna,Virya,Vipaka,Visarpa.

 

Important Formulations containing Saccharum munja.27, 28

There are number of Ayurvedic formulations containing Saccharum Munja manufactured and marketed  by  Ayurvedic companies such as Parvek and Aimil Pharaceuticals (India) Ltd. Table 4 shows the different formulations containing Saccharum munja as an active ingredint.

 

CONCLUSION:

It is concluded from this review that the different parts of Saccharum munja contain nutritive elements like sodium, potassium, calcium, magnesium, chloride, bicarbonates, iron, phosphate and sulphate which are responsible for its medicinal importance.  Traditionally the plant was being used to stop bleeding wounds, in fever and inflammation. It was found that the different parts of plant has been used to treat burning sensations, thrist, herpes, dyspepsia, dyscaria,                        erysipelas, urinary complaints and diseases of eyes. The root of the plant is used in dysuria, giddiness and vertigo and is an active ingredint of different ayurvedic formulations.

 

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Received on 18.02.2010       Modified on 28.02.2010

Accepted on 08.03.2010      © RJPT All right reserved

Research J. Pharm. and Tech.3 (3): July-Sept. 2010; Page 636-639