Emerging Trends in Multidisciplinary Research (ICETMR-2020) 15-16 May 2020 at Dhonburi Rajabhat University, Bangkok, Thailand (07-Feb-2020)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   13

Issue No. :  2

Year :  2020

Pages :   653-658

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Analysis of Chemical Constituents and Antiparasitic Activities of the Extracts of Imperata cylindrica

Address:   P. B. Lalthanpuii, Zarzokimi, K. Lalchhandama*
Department of Life Sciences, Pachhunga University College, Aizawl 796001, Mizoram, India
*Corresponding Author
DOI No: 10.5958/0974-360X.2020.00125.0

With little known pharmacological potentials, Imperata cylindrica is infamous as an invasive grass. But to the Mizo people, the rhizome-root part is a convenient and potent remedy for intestinal helminthiasis. It is an acclaimed effective deworming agent against both tapeworm and roundworm infections, which makes it more interesting for the fact that antiparasitic drugs are usually active against a particular group of helminthic worms. GC-MS analysis of the chloroform extract indicated the presence of 13 volatile compounds, among which trans-13-Octadecenoic acid was by far, at relative abundance of 98.4%, the most abundant. There were 17 compounds in the petroleum ether extract with n-hexadecanoic acid at relative abundance of 99.7% is the major compound. Biologically active compounds such as 2-methoxy-4-vinylphenol, 6-methylenebicyclo [3.2.0] hept-3-en-2-one, campesterol, and stigmasterol were detected. An in vitro test showed that both the extracts were effective against the tapeworm Raillietina echinobothrida but only the chloroform at the highest concentration (20 mg/ml) was effective on the roundworm Ascaridia galli. These data imply that the plant extracts are a potential source of antiparasitic compounds.
Imperata cylindrica, GC-MS, parasite, tapeworm, roundworm.
P. B. Lalthanpuii, Zarzokimi, K. Lalchhandama. Analysis of Chemical Constituents and Antiparasitic Activities of the Extracts of Imperata cylindrica. Research J. Pharm. and Tech 2020; 13(2):653-658.
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