2nd International Conference on Fostering Interdisciplinary Research In Health Sciences (ICFIRHS) 2019 (01-May-2019)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   12

Issue No. :  5

Year :  2019

Pages :   2116-2122

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Analysis of Copper (II) in Pharmaceutical Products using Micelle form with the Turbidity Method



Address:   Shaymaa Ibrahim Saeed1, Ahmed Fadhil Khudhair2*, Sawsan Khudhair Abbas3 ,Hasan F. Alesary4
Chemistry Department, College of Science, University of Kerbala, Karbala, Iraq
*Corresponding Author
DOI No: 10.5958/0974-360X.2019.00351.2

ABSTRACT:
A modern and easy procedure performed using the turbidity method for the pre-concentration and estimating of Cu (II) in pharmaceutical samples. The limited solubility complex formed by the reaction of copper ions with cysteine and SDS as the surfactant. The copper content measured using the turbidity method. The effect of chemical and physical parameters including grouping of the ligand, SDS, pH, equilibration temperature and time and effect of salting are studied. The analytical qualities of the technique have been determined, which includes linear range (the range was between 0.158 -47.625µgmL 1), the coefficient of turbidity (k=13.21), limit of detection (LOD=0.1767 µg ml 1nd LOQ=0.5355 µg mL 1).All values are calculated using statistical programs, but the detection limit for Cu(II) ions based on eight times the standard deviation of the blanks (N:8) characterized as 3Sb/m (where Sb is the standard deviation of the blank and m is the slope of the calibration curve) is 0.0096µg mL-1 (3s). The method employed successfully for the determination of Cu2+ in different local pharmaceutical formations.
KEYWORDS:
Copper in Pharmaceutical Products, Turbidity, Micelle.
Cite:
Shaymaa Ibrahim Saeed, Ahmed Fadhil Khudhair, Sawsan Khudhair Abbas ,Hasan F. Alesary. Analysis of Copper (II) in Pharmaceutical Products using Micelle form with the Turbidity Method. Research J. Pharm. and Tech. 2019; 12(5):2116-2122.
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