2nd International Conference on Fostering Interdisciplinary Research In Health Sciences (ICFIRHS) 2019 (01-May-2019)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   12

Issue No. :  3

Year :  2019

Pages :   1181-1184

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Pharmacological Evaluation of Leaf Extract of Terminalia bellerica with Moringa oleifera for its Synergistic Action on Anti-diabetic Activity and Anti-inflammatory Activity in Rats



Address:   Sk. Karishma*, K. Lakshmi, D. Eswar Tony, A. Narendra Babu, Rama Rao Nadendla
Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Guntur. Andhra Pradesh
*Corresponding Author
DOI No: 10.5958/0974-360X.2019.00195.1

ABSTRACT:
Aim and Objective: To evaluate the pharmacological action of leaf extract of Terminalia bellerica with Moringa oleifera for its synergistic action on Anti Diabetic activity and Anti-inflammatory activity in rats. Methodology: The Pharmacological evaluation of standardized aqueous extract of the leaves of Terminalia bellerica with Moringa oleifera was carried by using the following Stimuli models: a)Antidiabetic activity by Streptozotocin Induced Diabetes, b) Anti-inflammatory activity by Egg Albumin Induced Paw Edema. Results: The parameters of various activities to assess anti diabetic and anti inflammatory activities were evaluated and found That, The combination of extracts possess a better response then alone. Conclusion: The aqueous leaf extract of the combination of Terminalia bellerica with Moringa oleifera has shown significant anti diabetic and anti-inflammatory activities when compared with standard and extract alone.
KEYWORDS:
Terminalia bellerica, Moringa oleifera, Anti diabetic activity, Anti-inflammatory activity, Digital Plethysmometer, Glucometer.
Cite:
Sk. Karishma, K. Lakshmi, D. Eswar Tony, A. Narendra Babu, Rama Rao Nadendla. Pharmacological Evaluation of Leaf Extract of Terminalia bellerica with Moringa oleifera for its Synergistic Action on Anti-diabetic Activity and Anti-inflammatory Activity in Rats. Research J. Pharm. and Tech. 2019; 12(3): 1181-1184.
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