2nd International Conference on Fostering Interdisciplinary Research In Health Sciences (ICFIRHS) 2019 (01-May-2019)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   12

Issue No. :  12

Year :  2019

Pages :   5837-5840

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Study of Anti-inflammatory and Anti-microbial activity of green nanoparticles prepared from the water extract of lettuce Lactuca sativa



Address:   Sundus H. Ahmed, Rasha S. Hameed, Alyaa M. Yousif, Zena H. Gazar
Mustansiriyah University, College of Science, Biology Department
*Corresponding Author
DOI No: 10.5958/0974-360X.2019.01011.4

ABSTRACT:
In our current study, green nanoparticles were prepared using lettuce Lactuca sativa without using toxic chemicals. Visually, the formation of silver nanoparticles was confirmed by observing changes in color from pale yellow to dark brown. The peak absorption of the UV spectrophotometer was observed at 360 nm. Nanoparticles were characterized by SEM and FTIR analysis. Antimicrobial activity against Pseudomonas aeruginosa, Escherichia coli, Proteus vulgaris, a Bacillus subtls and Klebsiella pneumoneae, Candida spp and phytopathogenic Aspergillus niger; the prepared nanoparticles showed a high anti-inflammatory effect compared to the standard drug Profein. The results suggest that silver nanoparticles may have an important advantage compared to traditional antibiotics, and it was concluded the the nano particle accumulate the active component of Lactuca sativa may be for this it gives the highest scavenging activity.
KEYWORDS:
nanoparticles, silver, Lactuca sativa, SEM, FTIR.
Cite:
Sundus H. Ahmed, Rasha S. Hameed, Alyaa M. Yousif, Zena H. Gazar. Study of Anti-inflammatory and Anti-microbial activity of green nanoparticles prepared from the water extract of lettuce Lactuca sativa. Research J. Pharm. and Tech. 2019; 12(12): 5837-5840.
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