2nd International Conference on Fostering Interdisciplinary Research In Health Sciences (ICFIRHS) 2019 (01-May-2019)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   11

Issue No. :  1

Year :  2018

Pages :   121-125

ISSN Print :  0974-3618

ISSN Online :  0974-360X


Registration

Allready Registrered
Click to Login

Quantification of Itopride Hydrochloride from tablet dosage form by visible Spectroscopy



Address:   Salunke Poonam A.*, Kadam Lalit, Jaiswal Nikita, Jain Roshan, Patil Shital, Wagh Rupali, Dr. Barhate S. D.
Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner, Dist-Jalgaon.
*Corresponding Author
DOI No: 10.5958/0974-360X.2018.00023.9

ABSTRACT:
The present study to describe the Quantification of Itopride Hydrochloride from tablet dosage form by visible spectroscopy by applying principle of colorimetric study. It involves the measurement of the amount of ultraviolet (190-380 nm) or visible (380-800nm) radiation absorbed by a substance in solution. The final optimised method carried out on double beam UV-visible spectrophotometer (Shimadzu, model 1800) having two matched quartz cells with 1 cm light path by using Bromothymol blue of concentration 0.5% w/v solution. Itopride Hydrochloride detection wavelength was set at 479.40nm The linearity was found to be in the range of 10-50µg/ml. This method for the quantitative determination of the drug by validation in accordance with the International Conference on Harmonization. The proposed method is economic, simple, sensitive, reproducible, and accurate and no interference is observed due to common excipients of tablet. The proposed method was successfully applied to determination of Itopride hydrochloride in pharmaceutical formulations.
KEYWORDS:
Itopride Hydrochloride, UV-visible spectrophotometer, analytical method validation, acid-dye method.
Cite:
Salunke Poonam A., Kadam Lalit, Jaiswal Nikita, Jain Roshan, Patil Shital, Wagh Rupali, . Barhate S. D.. Quantification of Itopride Hydrochloride from tablet dosage form by visible Spectroscopy. Research J. Pharm. and Tech. 2018; 11(1): 121-125
[View HTML]      [View PDF]



Visitor's No. :   689120