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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   10

Issue No. :  3

Year :  2017

Pages :   693-695

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Screening of Antimicrobial Activity of tin Chlorophyllin from Morinda citrifolia L.



Address:   Pavithra. S1*, N. Banu 2
1Research Scholar, Department of Biotechnology, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Vels University, Chennai, Tamil Nadu, India.
2Associate Professor, Department of Biotechnology, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Vels University, Chennai, Tamil Nadu, India.
*Corresponding Author
DOI No: 10.5958/0974-360X.2017.00129.9

ABSTRACT:
Metallochlorophyllin, a water soluble analogue of the ubiquitous green pigment chlorophyll belongs to a group of compounds, porphyrins that contain a cheated metal ion in the center of the molecule. Tin chlorophyll in is the metallochlorophyllin with tin as its central metal ion and the phytol chains lost. The aim of the present study was to explore the antimicrobial activity of tin chlorophyll in from the leaves of Morinda citrifolia L. The leaves were collected and the tin chlorophyll in was extracted. The extracted tin chlorophyll in was subjected for antimicrobial study by disc diffusion method. The test organisms include Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella typhi, Pseudomonas aeroginosa, Aspergillus niger, Rhizopus microsporus. The inhibition zones were detected and were calculated for the various organisms. The Minimal Inhibitory Concentration (MIC) was also determined and found to be 125µg/ml (Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeroginosa) and 250µg/ml (Escherichia coli, Salmonella typhi). The results of the present study conclude that tin chlorophyll in from the leaves of Morinda citrifolia L. showed significant antimicrobial activity.
KEYWORDS:
Metallochlorophyllin, Tin chlorophyll in, Antibacterial, Antifungal, MIC.
Cite:
Pavithra. S, N. Banu . Screening of Antimicrobial Activity of tin Chlorophyllin from Morinda citrifolia L. Research J. Pharm. and Tech. 2017; 10(3): 693-695.
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