List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235) (19-Apr-2017)        | List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research (22-Jan-2017)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   10

Issue No. :  3

Year :  2017

Pages :   765-768

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Effects of L-lysine-α-Oxidase from Trichoderma In Vitro Experiments on the model of Viruses as Sindbis, Tick-borne encephalitis, West Nile, Tahyna and Dhori



Address:   V. F. Larichev¹, I. P. Smirnova², S. P. Syatkin², G. I. Myandina², S. M. Chibisov², Е. А. Ryskina²
¹Federal State Budgetary Institution “Research Institute of Epidemiology and Microbiology named after Honorable Academician N. F. Gamaleya”, 16 Gamalei Str, Moscow
²Medical Department of Medical Institute of Peoples’ Friendship University of Russia, 3 Ordzhonikidze Str., Moscow
*Corresponding Author
DOI No: 10.5958/0974-360X.2017.00143.3

ABSTRACT:
For the first time we studied the effect of the anticancer drug L-lysine-a-oxidase, obtained from culture liquid of Trichoderma harzianum Rifai F-180. In vitro experiments we established the high activity of L-lysine-a-oxidase in a model of tick-borne encephalitis and the lack of activity against viruses Sindbis, West Nile, Tahyna and Dhori.
KEYWORDS:
L-lysine-α-oxidase, arboviruses, tick-borne encephalitis, cytopathic effect, antiviral activity.
Cite:
V. F. Larichev, I. P. Smirnova, S. P. Syatkin, G. I. Myandina, S. M. Chibisov, Е. А. Ryskina. Effects of L-lysine-α-Oxidase from Trichoderma In Vitro Experiments on the model of Viruses as Sindbis, Tick-borne encephalitis, West Nile, Tahyna and Dhori. Research J. Pharm. and Tech. 2017; 10(3): 765-768.
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