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Research Journal of Pharmacy and Technology
ISSN: 0974-360X(Online), 0974-3618(Print)
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List of Refereed Journals published by UGC, New Delhi on 28-03-2017-- AJRC (Sr. No.-1025); AJM (Sr. No.-2497); RJET (Sr. No.-7220); RJPP (Sr. No.- 7232): RJPPD (Sr. No.- 7234); RJPT (Sr. No.-7235)
List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Research
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New Analytical Techniques for the Determination of Epalrestat in Pharmaceutical Dosage forms by Spectrophotometry
Mukthinuthalapati Mathrusri Annapurna
Mukthinuthalapati Mathrusri Annapurna*, Malineni Sushmitha , Kunala Anusha
Department of Pharmaceutical Analysis and Quality Assurance, GITAM Institute of Pharmacy, GITAM University, Visakhapatnam, India
Epalrestat is an aldose reductase inhibitor. Three simple, precise and accurate Spectrophotometric methods have been developed for the determination of Epalrestat in pharmaceutical formulations. Spectrophotometric analysis was performed and linearity was observed over the concentration range 0.1-25, 0.5-20 and 0.5-20 µg/ml in phosphate buffer (pH 5.0), phosphate buffer (pH 7.0) and borate buffer (pH 9.0) respectively. All the three methods were validated and can be used for the determination of Epalrestat in pharmaceutical formulations (Tablets).
Epalrestat, phosphate buffer and borate buffer, Spectrophotometry, Validation.
Mukthinuthalapati Mathrusri Annapurna, Malineni Sushmitha , Kunala Anusha. New Analytical Techniques for the Determination of Epalrestat in Pharmaceutical Dosage forms by Spectrophotometry. Research J. Pharm. and Tech. 2017; 10(3): 739-742.
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