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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   10

Issue No. :  11

Year :  2017

Pages :   3981-3989

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Using Gas Chromatography-Mass Spectrometry (GC-MS) Technique for Analysis of Bioactive Compounds of Methanolic Leaves extract of Lepidium sativum



Address:   Hussein J. Hussein1, Imad Hadi Hameed*2, Mohammed Yahya Hadi 3
1Department of Biology, College of Science for women, University of Babylon, Iraq
2College of Nursing, University of Babylon, Iraq
3College of Biotechnology, Al-Qasim Green University, Iraq
*Corresponding Author
DOI No: 10.5958/0974-360X.2017.00723.5

ABSTRACT:
Cress (Lepidium sativum), sometimes referred to as garden cress to distinguish it from similar plants also referred to as cress (from old Germanic cresso which means sharp, spicy), is a rather fast-growing, edible herb. The objective of this study was analysis of the secondary metabolite products. Bioactives are chemical compounds often referred to as secondary metabolites. Ninteeth bioactive compounds were identified in the methanolic extract of Lepidium sativum. The identification of bioactive chemical compounds is based on the peak area, retention time molecular weight and molecular formula. GC-MS analysis of Lepidium sativum revealed the existence of the Glycerin, Monoethanolamine, 1-Deoxy-d-mannitol, 1-Nitro-2-propanol , 2-Butanamine , (S)-, Furfural, Allyl isothiocyanate , Paromomycin, 2-Hydroxy-2-(5-methylfuran-2-yl)1-phenylethanone , 3,6-Diazahomoadamantan-9-one Hydrazone , 2,3,4-Trimethoxycinnamic acid , 2-Naphthalenol , 2,3,4,4a,5,6,7-octahydro-1,4a-dimethyl-7-(2)- , cis-Vaccenic acid , 9-Octadecenamide , ?-Tocopherol , Phthalic acid , decyl oct-3-yl ester , Ergosta-5,22-dien-3-ol,acetate , ( 3ß,22E)- , Campesterol and Cholest-5-en-3-ol ,24-propylidene-,(3ß). GC-MS is widely used in pharmaceutical industries for analytical research and development, quality control, quality assurance, production, pilot plants departments for active pharmaceutical ingredients (API), bulk drugs and formulations.
KEYWORDS:
GC-MS, Bioactive Compounds, Leaves, Lepidium sativum.
Cite:
Hussein J. Hussein, Imad Hadi Hameed, Mohammed Yahya Hadi. Using Gas Chromatography-Mass Spectrometry (GC-MS) Technique for Analysis of Bioactive Compounds of Methanolic Leaves extract of Lepidium sativum. Research J. Pharm. and Tech 2017; 10(11): 3981-3989.
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