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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   9

Issue No. :  7

Year :  2016

Pages :   942-944

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Formulation, evaluation and release studies of Indomethacin Suppositories



Address:   Kalyani Dewangan1, Kushagra Nagori1, Mukesh Sharma1, Ajay Singh2, Sandhya Chandrakar1, Vandana Devi Sahu1, Garima Sharma1, Sujata Gupta1, Harsha Solanki1, Manisha Majumdar1, D. K. Tripathi1, Amit Alexander1, Ajazuddin1*
1Rungta College of Pharmaceutical Sciences and Research, Kurud Road Kohka, Bhilai, Chhattisgarh, India, 490024
2GD Rungta College of Science and Technology, Kurud Road Kohka, Bhilai, Chhattisgarh, India, 490024
*Corresponding Author
DOI No: 10.5958/0974-360X.2016.00181.5

ABSTRACT:
Indomethacin suppositories were prepared by using water soluble bases. All the prepared suppositories were evaluated for various physical parameters like weight variation, hardness, Liquefaction time. In-vitro release study was performed USP type I apparatus (Basket type) using phosphate buffer pH 7.4 as dissolution media. The suppositories prepared were within permissible range of all physical parameters.
KEYWORDS:
Indomethacin, suppositories, Liquefaction time.
Cite:
Kalyani Dewangan, Kushagra Nagori, Mukesh Sharma, Ajay Singh, Sandhya Chandrakar, Vandana Devi Sahu, Garima Sharma, Sujata Gupta, Harsha Solanki, Manisha Majumdar, D. K. Tripathi, Amit Alexander, Ajazuddin. Formulation, evaluation and release studies of Indomethacin Suppositories. Research J. Pharm. and Tech. 2016; 9(7):942-944.
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