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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   9

Issue No. :  2

Year :  2016

Pages :   128-130

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Screening of Antibacterial Activity In Vitro of Eryngium creticum



Address:   Oussama Mansour1*, Manal Darwish2, Ghenwa Ismail3, Rim Harfouch4, Rabab Shikh Ali2, Zain Deeb2
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al Andalus University, Tartous, Syria.
2Department of Pharmacognosy, Faculty of Pharmacy, Al Andalus University, Tartous, Syria.
3Department of Pharmaceutics, Faculty of Pharmacy, Al Andalus University, Tartous, Syria.
4Department of Microbiology, Faculty of Pharmacy, Al Andalus University, Tartous, Syria.
*Corresponding Author
DOI No: 10.5958/0974-360X.2016.00020.2

ABSTRACT:
This study was conducted to evaluate the antimicrobial activity of tow extract of Eryngium creticum plant belonging to the Apiaceae family collected from the coastal surrounding, Tartous, Syria. Many efforts have been made to discover new antimicrobial activity from a variety of sources such as micro-organisms , animals and plants. One such source is Folk medicine. Systematic screening of them may result in the discovery of new effective compounds. These extracts were prepared with polar solvent (methanol and ethanol) by steeping extraction method. The antimicrobial activity of the extracts was assessed using the disk diffusion method against gram-positive (Staphylococcus aureus), and gram-negative (Escherichia coli) bacteria. The methanolic extracts of Eryngium creticum have shown antimicrobial activity against tested bacteria. The activity was compared with potent broad spectrum antibiotics such as Cefipime, Amecasine and ceftriaxon.
KEYWORDS:
Eryngium Creticum, disk diffusion method, antimicrobial activity, extracts, Staphylococcus aureus, Escherichia coli.
Cite:
Oussama Mansour, Manal Darwish, Ghenwa Ismail, Rim Harfouch, Rabab Shikh Ali, Zain Deeb. Screening of Antibacterial Activity In Vitro of Eryngium creticum. Research J. Pharm. and Tech. 9(2): Feb., 2016; Page 128-130.
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