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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   8

Issue No. :  9

Year :  2015

Pages :   1247-1249

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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A novel methodology for the synthesis of teriflunomide using hydrotropes as a reaction media



Address:   Yashwant S. Surve*, Dharmesh G. Panchal, and R.S Lokhande
School of Basic science, Department of Chemistry. Jaipur National University, Jaipur
*Corresponding Author
DOI No: 10.5958/0974-360X.2015.00226.7

ABSTRACT:
This paper describes the synthesis of teriflunomide (Active pharmaceutical ingredients), used in the treatment of multiple sclerosis. The synthesis of teriflunomide was carried out using three different hydrotropes. The effect of these hydrotropes on yield, quality of product was studied at two different temperature conditions.
KEYWORDS:
Cumene sulfonic acid (CSA), Xylene sulfonic acid (XSA), p-toluene sulfonic acid (PTSA).
Cite:
Yashwant S. Surve, Dharmesh G. Panchal, R.S Lokhande. A novel methodology for the synthesis of teriflunomide using hydrotropes as a reaction media. Research J. Pharm. and Tech. 8(9): Sept, 2015; Page 1247-1249.
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