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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   8

Issue No. :  5

Year :  2015

Pages :   517-519

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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GC-MS/MS Study of Parthenium hysterophorus L(N. Am) stem, Antimicrobial activity



Address:   M. Krishnaveni1 *, M. Kalaivani2, C. Ragina Banu2, G. Krishna Kumari2
1Assistant Professor, Department of Biochemistry, School of Bio-Sciences, Periyar University, Salem 2M.Phil Students, Department of Biochemistry, School of Bio-Sciences, Periyar University, Salem *Corresponding Author
DOI No: 10.5958/0974-360X.2015.00086.4

ABSTRACT:
15 species of Parthenium are available under this genus. Parthenium hysterophorus belong to the family of Asteracea. Since, plant forms a fundamental raw material for the development of therapeutic drug, the phytocomponents of plants are vital tool for the treatment and cure. So, the present work was decided to study the components in ethanol extract of Parthenium hysterophorus stem through GC-MS/MS and its antimicrobial activity. The results of GC-MS/MS showed highest peak for Aciphyllene, Stigmasteryltosylate, Benzophenone, Stigmasterol, 4-Nitrophenyl laurate. Compounds such as Azulene, 1,2,3,5,6,7,8,8a-octahydro-1,4-dimethyl-7-(1-methylethenyl)-, [1S-(1a,7a,8aß)]-, Bicyclo[3.1.0]hexan-2-one, 1,5-bis(1,1-dimethylethyl)-3,3-dimethyl-, 1,2-Benzenediol, mono(methylcarbamate), 2,5-Dihydroxyacetophenone, bis(trimethylsilyl) ether, 12-Tridecynoic acid, methyl ester, Phenol, 3,4-dimethoxy-, 4-Acetoxy-3-methoxystyrene, Benzoic acid, 4-methyl-2-trimethylsilyloxy-, trimethylsilyl ester, 12-Tridecynoic acid, methyl ester, Tetradecanoic acid shows moderate peak area percent. The results of antimicrobial activity shows that antimicrobial activity was observed with Escherichia coli, Aspergillus niger, Candida albicans while, Staphylococcus aureus showed no zone of inhibition.
KEYWORDS:
Antibacterial, Antifungal, Parthenium, Phytocontituents, GC-MS/MS.
Cite:
M. Krishnaveni, M. Kalaivani, C. Ragina Banu, G. Krishna Kumari. GC-MS/MS Study of Parthenium hysterophorus L(N. Am) stem, Antimicrobial activity. Research J. Pharm. and Tech. 8(5): May, 2015; Page 517-519.
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