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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   8

Issue No. :  11

Year :  2015

Pages :   1548-1554

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Formulation and evaluation of hydroalcoholic extract of Berberis aristata DC. and Punica granatum Linn. for anti-acne action

Address:   Karodi Revan1* Mahendrakumar C.B.2, Bhise Kiran3
1Padm. Dr. D.Y. Patil College of Pharmacy, Akurdi, Pune, Maharashtra – 411044. (India)
2St. Mary College of Pharmacy, Secunderabad, Andhra Pradesh – 500085. (India)
3MCE Socy’s Allana College of Pharmacy, Camp, Pune, Maharashtra- 411001. (India)
*Corresponding Author
DOI No: 10.5958/0974-360X.2015.00276.0

Traditional medicine is the synthesis of therapeutic experience of generations of practicing physicians of indigenous systems of medicine. Throughout the history of mankind, many infectious diseases have been treated with herbals. The traditional medicine is increasingly solicited through the traditional practitioners and herbalists in the treatment of infectious diseases. Two such folklore plants which have number of traditional uses are Punica granatum linn, and Berberis aristata DC of punicaceae and berberidaceae family respectively. Berberis aristata has played a prominent role in herbal healing for more than 2,500 years. The ancient Egyptians used it to prevent plagues. In Indias it is used for dysentery, antibacterial infection, inflammations, high blood pressure, and for abnormal uterine bleeding. Decoction of roots of Berberis aristata is used for skin troubles and in blood purification. The synergistic action of berberine chemical constituents are to be superior to that of single constituents. Acne vulgaris is the most common dermatological disorder amongst teenagers which they dont like. Therefore as per the claim into the ancient text the current research was focused on formulation and evaluation of extract of Punica granatum linn. and Berberis aristata DC. for antiacne screening. The fingerprinting and spectroscopic analysis of the extract was determined. The extracts were also evaluated for antioxidant and lipid peroxidation activity by 1, 1- diphenyl-2-picryl-hydrazyl and TBARs method respectively. The study throws a limelight on use of Punica granatum linn. and Berberis aristata DC.in prevention and treatment of acne with the goal of elucidating the active potential compounds.
Berberis aristata DC, Broth dilution, cup plate method, High performance thin layer chromatography, 1- diphenyl-2-picryl-hydrazyl method.
Karodi Revan, Mahendrakumar C.B., Bhise Kiran. Formulation and evaluation of hydroalcoholic extract of Berberis aristata DC. and Punica granatum Linn. for anti-acne action. Research J. Pharm. and Tech. 8(11): Nov., 2015; Page 1548-1554.
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