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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   7

Issue No. :  4

Year :  2014

Pages :   425-428

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Allium kurrat and Eruca sativa are Natural agents for Inhibition and Eradication of Enterohemorrhagic Escherichia coli O157:H7 Biofilm



Address:   Hisham A. Abbas1*, Mona A. El-Sayed1, Mohamed M. Kamel2, Lina Gamil1
1Department of Microbiology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt
2Department of Water Microbiology, National Research Center, Cairo, Egypt
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Allium kurrat and Eruca sativa extracts exerted antimicrobial and antibiofilm activities against Escherichia coli O157:H7. Both extracts could inhibit planktonic growth at 2.5 mg/ml. The biofilm inhibition was investigated at different sub-inhibitory concentrations. Allium kurrat extract showed a statistically significant higher biofilm inhibiting activity than that of Eruca sativa extract. The percentage of biofilm inhibition of Allium kurrat extract ranged between 65.42±0.18 and 50.65±0.09 at 1/2MIC and 1/16 MIC, respectively. At 1/2MIC, the percentage of biofilm inhibition of Eruca sativa extract was 59.37±0.29, while at 1/16 MIC Eruca sativa extract inhibited biofilm formation by 40.17±0.05. Allium kurrat extract showed higher biofilm eradicating activity than Eruca sativa extract. E. coli O157:H7 biofilm was eliminated by Allium kurrat extract at 1/8MIC, while similar activity was observed at MIC of Eruca sativa extract. These results suggest the use of Allium kurrat and Eruca sativa extracts to control Escherichia coli O157:H7 biofilm.
KEYWORDS:
Escherichia coli O157:H7, biofilm inhibition, biofilm eradication, Eruca sativa, Allium Kurrat
Cite:
Hisham A. Abbas, Mona A. El-Sayed, Mohamed M. Kamel, Lina Gamil. Allium kurrat and Eruca sativa are Natural agents for Inhibition and Eradication of Enterohemorrhagic Escherichia coli O157:H7 Biofilm . Research J. Pharm. and Tech. 7(4): April, 2014; Page 425-428.
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