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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   6

Issue No. :  9

Year :  2013

Pages :   967-973

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Chemical Imaging: An overview and its Applications in Pharmaceutical Processes and Quality Control



Address:   Atmaram Tambe*, Vinayak Dalvi, Daksha Parmar, Vineeta Khanvilkar and Dr. Vilasrao Kadam
Department of Quality Assurance, Bharati Vidyapeeth’s College of Pharmacy, C.B.D. Belapur, Navi Mumbai-400614, Maharashtra, India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Chemical imaging technique is very useful tool for pharmaceutical quality control and optimization of pharmaceutical processes. It is a fusion of vibrational spectroscopy and imaging techniques. Real time process control is major advantage of this technique. Studying spatial distribution and localizing different components in multicomponent samples is a gift of chemical imaging. Advanced image processing and multivariate statistical methods are used to extract the useful information from the chemical images. Chemical imaging is applied for many quality control tests which are discussed in this article. Defective articles can be identified and removed from the bulk with the help of chemical imaging and thus minimizing the risk of defective sample getting into the finished product line. Thus it can be promising tool with faster image acquisition in a lower cost with better image processing tools in near future.
KEYWORDS:
Chemical Imaging, Real time process control, spatial distribution, multicomponent samples and multivariate statistical methods.
Cite:
Atmaram Tambe, Vinayak Dalvi, Daksha Parmar, Vineeta Khanvilkar, Vilasrao Kadam. Chemical Imaging: An overview and its Applications in Pharmaceutical Processes and Quality Control. Research J. Pharm. and Tech. 6(9): September 2013; Page 967-973.
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