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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   6

Issue No. :  5

Year :  2013

Pages :   544-549

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Antibacterial Activity of Pseudoceratina purpurea - A Marine Sponge from Andaman



Address:   Suman T1, Kaleeswaran B2, Titus Immanuel3, Dam Roy S1, Krishnan P1*
1Central Agricultural Research Institute (CARI), Port Blair, Andaman. India
2Centre for Research and Development, PRIST University, Thanjavur, Tamil Nadu, India.
3Zoological Survey of India, Andaman and Nicobar Regional Centre, Port Blair, Andaman. India
*Corresponding Author
DOI No: Not Available

ABSTRACT:
The sponge Pseudoceratina purpurea associated bacteria from Pongibalu region of Andaman islands, India and isolate the methanolic extract of P. purpurea for identifying the antibacterial effect against certain pathogenic bacteria. Standard characterization and biochemical methods were employed for identifying the sponge associated bacteria. Antibacterial assay and micro broth dilution test for minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were subjected to evaluate the efficacy of P. purpurea extract against several gram positive and gram negative bacteria. Associated bacteria of P. purpurea, 75% were gram negative bacteria except Staphylococcus aureus, Bacillus subtilis and Proteus vulgaris were not susceptible to the sponge extract in well diffusion method. Minimum concentration effect was found in Bacillus thermophilus and Klebsiella pneumoniae against the P. purpurea extract. Overall study apparently showed that the organic extracts of this sponge might be a promising source of secondary metabolites and ascription of toxic metabolites from associated bacteria to find new and useful medicines to treat human and veterinary infections.
KEYWORDS:
Pseudoceratina purpurea, sponge, Pongibalu, Andaman, antibacterial.
Cite:
Suman T, Kaleeswaran B, Titus Immanuel, Dam Roy S, Krishnan P. Antibacterial Activity of Pseudoceratina purpurea - A Marine Sponge from Andaman. Research J. Pharm. and Tech6(5): May 2013; Page 544-549.
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