2nd International Conference on Fostering Interdisciplinary Research In Health Sciences (ICFIRHS) 2019 (01-May-2019)        |

Journal :   Research Journal of Pharmacy and Technology

Volume No. :   6

Issue No. :  3

Year :  2013

Pages :   2238-239

ISSN Print :  0974-3618

ISSN Online :  0974-360X


Registration

Allready Registrered
Click to Login

Assessment of Guggul Gum as a Binding Agent in Tablet Formulations



Address:   Upadhye Mohini*, Raut Pallavi, Dhole Shashikant, Kulkarni Nilesh
P. E. S.’s Modern College of Pharmacy (For Ladies), Moshi, Pune 412 105
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Guggul gum has been evaluated as a binder for Pharmaceutical dosage forms. No significant work has been reported on guggul gum to use it as a tablet binder. Paracetamol granules were prepared by wet granulation technique. The binder concentrations used in the formulations were 2, 4, 6 and 8 % w/w. the evaluation of granules showed 0.65 to 0.70 mm particle size, 28.15 to 29.16 º angle of repose. Tablets were prepared and its evaluation showed 1.3 to 0.9% friability, hardness about 7 kg/cm2 10 to 20 min disintegration time and more than 90% dissolution in 90 min. Tablet at 8 % w/w binder concentration showed more optimum results as tablet binder. Guggul gum was found to be useful for the preparation of uncoated tablet dosage form.
KEYWORDS:
Guggul gum, Binder, Evaluation.
Cite:
Upadhye Mohini, Raut Pallavi, Dhole Shashikant, Kulkarni Nilesh. Assessment of Guggul Gum as a Binding Agent in Tablet Formulations. Research J. Pharm. and Tech. 6(3): March 2013; Page 238-239.
[View HTML]      [View PDF]



Visitor's No. :   645206