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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   6

Issue No. :  3

Year :  2013

Pages :   2238-239

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Assessment of Guggul Gum as a Binding Agent in Tablet Formulations

Address:   Upadhye Mohini*, Raut Pallavi, Dhole Shashikant, Kulkarni Nilesh
P. E. S.’s Modern College of Pharmacy (For Ladies), Moshi, Pune 412 105
*Corresponding Author
DOI No: Not Available

Guggul gum has been evaluated as a binder for Pharmaceutical dosage forms. No significant work has been reported on guggul gum to use it as a tablet binder. Paracetamol granules were prepared by wet granulation technique. The binder concentrations used in the formulations were 2, 4, 6 and 8 % w/w. the evaluation of granules showed 0.65 to 0.70 mm particle size, 28.15 to 29.16 º angle of repose. Tablets were prepared and its evaluation showed 1.3 to 0.9% friability, hardness about 7 kg/cm2 10 to 20 min disintegration time and more than 90% dissolution in 90 min. Tablet at 8 % w/w binder concentration showed more optimum results as tablet binder. Guggul gum was found to be useful for the preparation of uncoated tablet dosage form.
Guggul gum, Binder, Evaluation.
Upadhye Mohini, Raut Pallavi, Dhole Shashikant, Kulkarni Nilesh. Assessment of Guggul Gum as a Binding Agent in Tablet Formulations. Research J. Pharm. and Tech. 6(3): March 2013; Page 238-239.
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