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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   6

Issue No. :  3

Year :  2013

Pages :   313-320

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Liquisolid compacts: A novel approach to enhance the dissolution



Address:   Jignesh Solanki*, Dhiren Daslaniya, Ghanshyam Patel, Bhavin Bhimani, Upendra Patel, Darshan Kamani
Arihant School of Pharmacy & BRI, Uvarsad, Gandhinagar-382421.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Liquisoild technique is a novel concept for delivery of drugs through oral route. This approach of delivering drugs is suitable mostly for lipophilic drugs and poorly or water insoluble drugs. This approach is suitable for immediate or sustain release formulations. Design and formulation of this approach is prescribed according to new mathematical model given by Spires et al. Increasing the solubility by using a non-volatile solvent which is suitable for drug, their by dissolving the drug in the non volatile solvent and this is termed as liquid medicament . Blending the liquid medicament with mixture of carrier and coating material, liquid medicament can be converted into non adhere, dry looking powder with acceptable flow properties and compression behavior using suitable excipients and tabletting by direct compression method.
KEYWORDS:
Liquisolid tablets, Dissolution enhancement, coating material, carrier and solvents.
Cite:
Jignesh Solanki, Dhiren Daslaniya, Ghanshyam Patel, Bhavin Bhimani, Upendra Patel, Darshan Kamani. Liquisolid compacts: A novel approach to enhance the dissolution. Research J. Pharm. and Tech. 6(3): March 2013; Page 313-320.
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