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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   6

Issue No. :  11

Year :  2013

Pages :   1240-1241

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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In Vitro Cytotoxic Activity of Alcoholic Extract of Aristolochia indica



Address:   V.A. Kangralkar1* and A.R. Kulkarni2
1Maratha Mandal’s College of Pharmacy, Belgaum Karnataka, 1Research Scholar, Karpagam University Coimbatore.
2Department of Pharmacology, SET’s College of Pharmacy, Dharwad- 580 002, India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Aristolochia indica root extract (alcoholic) was screened for its antitumor activity on proliferation of HT29 colon cancer cell line. The activity was determined by microculture tetrazolium viability (MTT) assay. The different concentrations (100, 50, 25, 12.5, 6.25and 3.125 µgram/ml) were taken and cells were exposed with the extract. The % cytotoxicity produced in MTT assay at100 Microgram/ml was 69.21 with IC50 of 28.56 . From these results it was observed that alcoholic extract of Aristolochia indica root has significant cytotoxic activity.
KEYWORDS:
Aristolochia indica root, MTT assays, cytotoxicity, IC50.
Cite:
V.A. Kangralkar, A.R. Kulkarni. In Vitro Cytotoxic Activity of Alcoholic Extract of Aristolochia indica. Research J. Pharm. and Tech. 6(11): November 2013; Page 1240-1241.
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