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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   6

Issue No. :  10

Year :  2013

Pages :   1127-1130

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Evaluation of Hepatoprotective Activity of Rhizomes of Curculigo orchioides Gaertn



Address:   G. Babu*, N. K. Shalima, T. A. Divya, T. Divya
Department of Pharmaceutical Chemistry, Devaki Amma Memorial College of Pharmacy, Chelembra 673634, Malappuram District, Kerala
*Corresponding Author
DOI No: Not Available

ABSTRACT:
The present study was conducted to evaluate the hepatoprotective activity of ethyl acetate extract of rhizomes of Curculigo orchioides. The extract at the dose of 200 mg/kg and 400 mg/kg b. wt. was tested for its hepatoprotection, by inducing hepatotoxicity with CCl4 in Wistar albino rats and using silymarin (100 mg/kg) as the reference standard. Biochemical parameters like, SGOT, SGPT, SALP and serum bilirubin were determined to assess the hepatoprotective effect. The extract has shown significant hepatoprotection in albino rats in reducing SGOT, SGPT, SALP and serum bilirubin levels.
KEYWORDS:
Antioxidant activity, hepatoprotection, Curculigo orchioides, DPPH assay, Free radical scavenging activity, Aging, Cirrhosis.
Cite:
G. Babu, N. K. Shalima, T. A. Divya, T. Divya. Evaluation of Hepatoprotective Activity of Rhizomes of Curculigo orchioides Gaertn. Research J. Pharm. and Tech. 6(10): October 2013; Page 1127-1130.
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