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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   6

Issue No. :  1

Year :  2013

Pages :   17-21

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Novel Approach in Transdermal Drug Delivery System: Transferosome



Address:   Miss. J.S. Pawar*, A. B. Roge, Dr. S. M. Vadvalkar
Nanded Pharmacy College, Opp-Kasturba Matru Seva Kendra, Shyam Nagar, Nanded -431605 Maharashtra
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Transdermal drug delivery system is emerging system as compared to oral and parenteral. In TDDS, patch system was developed to control the release of drug .Conventional transdermal drug delivery system achieved advantages over the oral and parenteral. Consequently a number of vesicular drug delivery systems such as liposomes, niosomes were been developed as novel transdermal drug delivery system. Firstly, it delivers the drug at a rate directed by the needs of the body, over the period of treatment. Secondly, it channels the active entity to the site of action. Liposomal as well as niosomal systems, are not suitable for transdermal delivery, because of their poor skin permeability, breaking of vesicles, leakage of drug, aggregation, and fusion of vesicles. To overcome these problems, a new type of carrier system called "transfersome", has recently been introduced, which is capable of transdermal delivery of low as well as high molecular weight drugs.Transferosome is a supramolecular entity that can pass through a permeability barrier and there by transport material from the application to the destination site. These are more elastic than standard liposomes. Transferosome has been widely used as a novel carrier for effective transdermal drug delivery. Transferosome enhances the penetration of most of the low as well as high molecular weight drugs, while in case of lipophilic drugs the entrapment efficiency can reach upto 90%. it is now widely used as a novel carrier for both systemic as well as topical delivery of drugs.
KEYWORDS:
TDDS, CTDDS, NTDDS, Transfersome, liposome.
Cite:
J.S. Pawar, A. B. Roge, S. M. Vadvalkar. Novel Approach in Transdermal Drug Delivery System: Transferosome. Research J. Pharm. and Tech. 6(1): Jan. 2013; Page 17-21.
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