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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  9

Year :  2012

Pages :   1209-1212

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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New Validated UV- Spectrophotometric Method for the Determination of Telmisartan in Bulk and Dosage Form



Address:   Santosh Kumar Vobbilireddi*, K. Sujana and Dr. A. Prameela Rani
University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Nagarjuna nagar, Guntur, (A.P), India – 522510
*Corresponding Author
DOI No: Not Available

ABSTRACT:
The present study describes a simple, accurate, precise and cost effective UV-Spectrophotometric method for the estimation of Telmisartan, an anti- hypertensive drug, in bulk and pharmaceutical dosage form. The solvent used throughout the method is a combination of DMF and 0.1N HCl in the ratio 1:9. The ?max or the absorption maxima of the drug was found to be 291nm. A linear response was observed in the range of 3- 15 µg/ml with a regression coefficient of 0.999. The method was then validated for different parameters. % Precision of method was find out as repeatability, day to day and analyst to analyst variation and shows the values within acceptable limit (R.S.D = 2 percentage).
KEYWORDS:
Telmisartan, UV-spectrophotometry, DMF, 0.1N HCl.
Cite:
Santosh Kumar Vobbilireddi, K. Sujana, A. Prameela Rani. New Validated UV- Spectrophotometric Method for the Determination of Telmisartan in Bulk and Dosage Form. Research J. Pharm. and Tech. 5(9): September 2012; Page 1209-1212.
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