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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  9

Year :  2012

Pages :   1145-1153

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Recent Advances in Coupling Technology in Analysis of Natural Product



Address:   T M Kalyankar*, A C Jadhav, S M Mhetre
Department of Pharmaceutical Chemistry, School of Pharmacy, Swami Ramanand Teerth Marathwada University, Nanded- 431 606.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Natural products have been the single most productive source of leads the development of drugs. The hyphenated technique is developed from the coupling of separation technique and on line spectroscopic detection technology. There is improvement in hyphenated r the last two decades have significantly broadened their application in the analysis of biomaterials especially natural products. In these article recent advances in the application of various hyphenated techniques e.g. LC-IR, LC-NMR, LC-MS, HPLC-NMR-MS, LC-ESI-MS, UPLC-MS, in the context of pre-isolation analysis of crud extract or fraction from various natural sources, isolation and online detection of natural products, chemotaxonomic studies, chemical fingerprinting, quality control of herbal products, dereplication of natural products and metabolomic studies are discussed here.
KEYWORDS:
LC-IR, LC-NMR, LC-MS, HPLC-NMR-MS, LC-ESI-MS, UPLC-MS, Natural products, Hyphenated techniques..
Cite:
T M Kalyankar, A C Jadhav, S M Mhetre. Recent Advances in Coupling Technology in Analysis of Natural Product. Research J. Pharm. and Tech. 5(9): September 2012; Page 1145-1153.
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