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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  8

Year :  2012

Pages :   1072-1075

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Synthesis and Antimicrobial Evaluation of 2-(1H-1,2,3-Benzotriazol-1-yl)-N-Phenylacetamide Derivatives



Address:   C. M. Jamkhandi*, John Intru Disouza.
Department of Pharmacy JJT University Jhunjhunu Rajasthan India.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
2-(1H-1,2,3-benzotriazol-1-yl)-N-phenylacetamide derivatives find useful as anti-infective agents and substitution of bentriazole produces more potent anti-infective agents. Derivatives of benzotriazole substituted 2-(1H-1,2,3-benzotriazol-1-yl)-N-phenylacetamide are synthesized and anti microbial activities have been measured against Norfloxacine and Ketoconazole as standards drugs. It is found that the derivatives from 1a to Va are shown to produce good anti microbial actions against, S. Aureus, S. Pygens, B. Subtilis, E.coli, P. Aerigenosa, C Albicanse, A Niger. The all the derivatives show satisfactory anti-microbial activities.
KEYWORDS:
Antibacterials, Anti fungals, benzotriazoles, N-phenyl acetamide derivatives.
Cite:
C. M. Jamkhandi, John Intru Disouza. Synthesis and Antimicrobial Evaluation of 2-(1H-1,2,3-Benzotriazol-1-yl)-N-Phenylacetamide Derivatives. Research J. Pharm. and Tech. 5(8): August 2012; Page 1072-1075.
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