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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  8

Year :  2012

Pages :   1112-1113

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Absorption Ratio Method for Simultaneous Estimation of Prochlorperazine Maleate and Pyridoxine Hydrochloride in Tablet



Address:   S. P. Wate, G. B. Bhagwat*, A. S. Mundhey and P. M. Bawankar
Sharad Pawar College of Pharmacy, Wanadongri, Hingna Road, Nagpur-441 110 (M.S.)
*Corresponding Author
DOI No: Not Available

ABSTRACT:
A simple, accurate, economical and reproducible procedure for simultaneous estimation of Prochlorperazine Maleate (PCM) and Pyridoxine Hydrochloride (PDH) in their tablet dosage form is described. The method involves absorbance of measurement at 267.5 nm (isobestic point) and 290.5 nm (?max of Pyridoxine Hydrochloride), in 0.3 N HCl. Both drugs obey Beer-Lambert’s law in concentration range of 1-5 µg/ml (PCM) and 5-25 µg/ml (PDH). The results of analysis have been validated statistically and by recovery studies.
KEYWORDS:
Prochlorperazine Maleate, Pyridoxine Hydrochloride, Validation.
Cite:
S. P. Wate, G. B. Bhagwat, A. S. Mundhey, P. M. Bawankar. Absorption Ratio Method for Simultaneous Estimation of Prochlorperazine Maleate and Pyridoxine Hydrochloride in Tablet. Research J. Pharm. and Tech. 5(8): August 2012; Page 1112-1113.
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