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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  6

Year :  2012

Pages :   800-804

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Study of Antidiarrhoeal Activity of Two Bangladeshi Medicinal Plants in Castor-oil Induced Diarrhoea



Address:   Dibyajyoti Saha*, Swati Paul
Department of Pharmacy, BGC Trust University Bangladesh, Chittagong.
*Corresponding Author
DOI No: Not Available

ABSTRACT:
A study was undertaken to evaluate the effect of methanolic plant extracts of Alpinia conchigera Griff. and Plumbago indica for their antidiarrhoeal potential against castor-oil induced diarrhoea in mice. The anti-diarrheal activity was determined by evaluating the latency period and diarrhoeal frequency by counting the faeces time and number of the test groups in comparison to the control and standard loperamide groups. The methanol extracts of the A. conchigera and P. indica at the doses of 250 and 500mg/kg reduced reduced induction time of diarrhoea and total weight of the faeces in comparison to the control group and the result was statistically significant. The result obtained establishes the efficacy of these plant extracts as antidiarrhoeal agents
KEYWORDS:
Antidiarrheal activity, castor oil, methanol extracts, induction time.
Cite:
Dibyajyoti Saha, Swati Paul. Study of Antidiarrhoeal Activity of Two Bangladeshi Medicinal Plants in Castor-oil Induced Diarrhoea. Research J. Pharm. and Tech. 5(6): June 2012; Page 800-804.
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