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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   5

Issue No. :  6

Year :  2012

Pages :   729-735

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Novel Ophthalmic Drug Delivery Approach: An Ophthalmic Inserts



Address:   Anjali Patel*, Dhara Patel, Nimisha Patel, Jayvadan Patel, Manish Patel, Anita Patel
Department of Pharmaceutics, Nootan Pharmacy College, Visnagar-384315,Gujarat, India
*Corresponding Author
DOI No: Not Available

ABSTRACT:
Ophthalmic drug delivery system is one of the most interesting and challenging approach facing the Pharmaceutical Scientist. The conventional ophthalmic drug delivery system like solution, suspension. Which shows poor bioavailability and therapeutic response because of rapid precorneal drug loss? Utilization of novel ophthalmic drug delivery system an ophthalmic inserts offers an advantage to prolonged drug residence time and a higher bioavailability with respect to conventional ophthalmic drug delivery system. Ocular inserts are sterile preparations, with a thin, multilayered, drug-impregnated, solid or semisolid consistency devices placed into cul-de-sac or conjunctiva sac. They are usually made up of polymeric vehicle containing drug. The therapeutic efficacy of an ocular drug can be greatly improved by prolonging its contact with the corneal surface. Newer ocular drug delivery systems are being explored to develop extended duration and controlled release strategy.
KEYWORDS:
Ocular inserts, Swelling index, Solvent casting method, Bio-erosion, Semi synthetic polymer.
Cite:
Anjali Patel, Dhara Patel, Nimisha Patel, Jayvadan Patel, Manish Patel, Anita Patel. Novel Ophthalmic Drug Delivery Approach: An Ophthalmic Inserts. Research J. Pharm. and Tech. 5(6): June 2012; Page 729-735.
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